Craniofacial Center, Division of Craniofacial and Surgical Care, Adams School of Dentistry, University of North Carolina at Chapel Hill.
Center for Pediatric Auditory and Speech Sciences, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE.
J Speech Lang Hear Res. 2021 Jan 14;64(1):30-39. doi: 10.1044/2020_JSLHR-20-00282. Epub 2020 Dec 2.
Purpose This study determined the time course of the emergence of prevocalic stop consonants in young children with cleft palate following surgical repair. Method A total of 120 children in four cohorts from three institutions were followed from 12 to 24 months of age: (a) 24 with repaired cleft lip and palate (CLP), (b) 36 with repaired cleft palate only (CP), (c) 33 without clefts but with histories of frequent otitis media and ventilation tubes (OM), and (d) 27 typically developing (TD) children without clefts or OM. Emergence of prevocalic stops and symbolic language skills were determined during administration of the Communication and Symbolic Behavioral Scales Developmental Profile. Parametric survival models were fitted with and without covariates-recruitment site, gender, maternal education level, middle ear status, language ability, and age at surgery for children with clefts-to describe the time course of the emergence of prevocalic stops. Results The estimated age at which 80% of children demonstrated prevocalic stop emergence was 15.0, 15.3, 18.9, and 21.8 months for TD, OM, CP, and CLP groups, respectively ( < .001, unadjusted model). Both CP and CLP cohorts had a significantly longer time to stop emergence than either the TD or OM cohorts, even after adjusting for covariates. Abnormal middle ear status, lower symbolic language ability, and older age at palatal surgery were significantly associated with delayed stop emergence. Conclusions Survival model estimates show that four out of five children with repaired cleft palate will achieve emergence of prevocalic stop consonants by 19-22 months of age, corresponding to 9-12 months following palate repair. Clinical implications are discussed.
本研究旨在确定接受腭裂修复手术后的腭裂儿童在何时出现前置塞音。
共有来自 3 个机构的 4 个队列的 120 名儿童接受了从 12 到 24 个月的随访:(a)24 名唇腭裂(CLP)修复患儿,(b)36 名单纯腭裂(CP)修复患儿,(c)33 名无腭裂但有频繁中耳炎和通气管(OM)病史的患儿,(d)27 名无腭裂或 OM 的典型发育(TD)儿童。在沟通和符号行为量表发育概况中进行了前置塞音和符号语言技能的出现评估。在有无协变量(招募地点、性别、母亲教育水平、中耳状况、语言能力和腭裂手术年龄)的情况下,拟合了参数生存模型,以描述前置塞音出现的时间过程。
TD、OM、CP 和 CLP 组中,80%的儿童表现出前置塞音的估计年龄分别为 15.0、15.3、18.9 和 21.8 个月(<0.001,未调整模型)。即使在调整了协变量后,CP 和 CLP 队列的停止出现时间也明显长于 TD 或 OM 队列。中耳异常、符号语言能力较低和腭手术年龄较大与延迟停止出现显著相关。
生存模型估计表明,接受腭裂修复手术的儿童中,有四分之三到五分之四将在 19-22 个月龄时出现前置塞音,这对应于腭裂修复后 9-12 个月。讨论了临床意义。