Suppr超能文献

从污水中提取新冠病毒(COVID-19)是否有助于控制曲线?

Will the extraction of COVID-19 from wastewater help flatten the curve?

机构信息

Centre for Environmental Management, Faculty of Natural and Agricultural Science, University of the Free State Bloemfontein, 9300, South Africa.

Centre for Environmental Management, Faculty of Natural and Agricultural Science, University of the Free State Bloemfontein, 9300, South Africa.

出版信息

Chemosphere. 2021 May;271:129429. doi: 10.1016/j.chemosphere.2020.129429. Epub 2021 Jan 5.

Abstract

With the potentially fatal effect of COVID-19 and its devastating impact on economies worldwide, some environmental scientist has suggested the use of waste from household sewage to trace the movement of SARS-CoV-2, within a given country. However, this approach is not without challenges where developing countries lack proper and adequate hygiene and sanitation, resulting in widespread defecation. Limited scientific research has been done to determine how many times a recently infected person can defecate and the quantification of SARS-CoV-2 found in a single expel. On the other hand, there is no detailed research to specify where the heavy viral load of SARS-CoV-2 can be found in human excreta. In this paper, we present some obstacles that this approach could face in the absence of an intense lockdown in developing nations such as sub-Saharan countries. To achieve this, we identify some research needs that will strengthen our understanding of the transmission, occurrence, and persistence of SARS-CoV-2 in sewage and wastewater, including the life-span that depends on temperature. A methodology to follow in the process of identifying a hotspot on a small scale using some mathematical distributions, including the normal distribution, log-normal distribution, and the most complex one known as Blancmange function, was presented with some examples. Our investigation showed that this method might have some challenges, especially in developing countries (sub-Sahara countries) where open latrine usage is very high. Some recommendations we suggested to ensure the efficiency of such a method on a small scale. However, in general, it is essential to note the extraction/detection method will not help more than the testing method used all over the world to trace SARS-CoV-2 -19 in humans.

摘要

由于 COVID-19 可能致命的影响及其对全球经济的毁灭性影响,一些环境科学家建议利用家庭污水中的废物来追踪 SARS-CoV-2 在一个特定国家内的传播轨迹。然而,这种方法并非没有挑战,因为发展中国家缺乏适当和充足的卫生和环境卫生条件,导致广泛的随地大小便。很少有科学研究来确定一个新感染的人可以排便多少次,以及在单次排便中发现的 SARS-CoV-2 的定量。另一方面,没有详细的研究来确定 SARS-CoV-2 的高病毒载量可以在人类排泄物中的哪个部位找到。在本文中,我们提出了在发展中国家(如撒哈拉以南非洲国家)没有严格封锁的情况下,这种方法可能面临的一些障碍。为此,我们确定了一些研究需求,这些需求将加强我们对 SARS-CoV-2 在污水和废水中的传播、发生和持续存在的理解,包括取决于温度的寿命。提出了一种使用一些数学分布(包括正态分布、对数正态分布和最复杂的 Blancmange 函数)在小规模上识别热点的方法,并提供了一些示例。我们的调查表明,这种方法可能存在一些挑战,特别是在发展中国家(撒哈拉以南非洲国家),那里开放式厕所的使用率非常高。我们建议了一些建议,以确保这种小规模方法的效率。然而,总的来说,必须注意到,提取/检测方法不会比全世界用于追踪人类 SARS-CoV-2-19 的检测方法更有帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c298/7784541/90b8358887c1/gr1_lrg.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验