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不能仅用 SNP 讲述的故事:植物群体中的 DNA 甲基化变异。

Stories that can't be told by SNPs; DNA methylation variation in plant populations.

机构信息

Department of Plant and Microbial Biology, University of Minnesota, Saint Paul, MN 55108, USA.

Department of Plant and Microbial Biology, University of Minnesota, Saint Paul, MN 55108, USA.

出版信息

Curr Opin Plant Biol. 2021 Jun;61:101989. doi: 10.1016/j.pbi.2020.101989. Epub 2021 Jan 11.

DOI:10.1016/j.pbi.2020.101989
PMID:33445144
Abstract

Epigenetic variation has been observed in many plant populations. This variation can influence qualitative and quantitative traits. A key question is whether there is novel information in the epigenome that is not captured by SNP-based genetic markers. The answer likely varies depending on the sources and stability of epigenetic variation as well as the type of population being studied. We consider the epigenetic variation in several plant systems and how this relates to potential for hidden information that could increase our understanding of phenotypic variation.

摘要

在许多植物种群中观察到了表观遗传变异。这种变异会影响定性和定量性状。一个关键问题是,表观基因组中是否存在 SNP 遗传标记无法捕捉到的新信息。答案可能因表观遗传变异的来源和稳定性以及所研究的种群类型而异。我们考虑了几种植物系统中的表观遗传变异,以及这与潜在隐藏信息的关系,这些信息可能增加我们对表型变异的理解。

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