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1
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.利用游离 DNA 中的甲基化特征进行敏感且特异的多癌种检测和定位。
Ann Oncol. 2020 Jun;31(6):745-759. doi: 10.1016/j.annonc.2020.02.011. Epub 2020 Mar 30.
2
Validation of Lung EpiCheck, a novel methylation-based blood assay, for the detection of lung cancer in European and Chinese high-risk individuals.基于甲基化的新型血液检测方法Lung EpiCheck在欧洲和中国高危个体中用于肺癌检测的验证。
Eur Respir J. 2021 Jan 14;57(1). doi: 10.1183/13993003.02682-2020. Print 2021 Jan.
3
Low molecular weight serum cell-free DNA concentration is associated with clinicopathologic indices of poor prognosis in women with uterine cancer.低分子量血清游离DNA浓度与子宫癌女性患者预后不良的临床病理指标相关。
J Transl Med. 2020 Aug 27;18(1):323. doi: 10.1186/s12967-020-02493-8.
4
Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging.在一项先进行自身抗体血液检测随后进行成像的随机试验中对肺癌进行早期诊断。
Eur Respir J. 2021 Jan 14;57(1). doi: 10.1183/13993003.00670-2020. Print 2021 Jan.
5
Circulating tumour cells as a potential biomarker for lung cancer screening: a prospective cohort study.循环肿瘤细胞作为肺癌筛查的潜在生物标志物：一项前瞻性队列研究。
Lancet Respir Med. 2020 Jul;8(7):709-716. doi: 10.1016/S2213-2600(20)30081-3.
6
Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention.血液检测结合 PET-CT 筛查癌症并指导干预的可行性。
Science. 2020 Jul 3;369(6499). doi: 10.1126/science.abb9601. Epub 2020 Apr 28.
7
Integrating genomic features for non-invasive early lung cancer detection.整合基因组特征进行非侵入性早期肺癌检测。
Nature. 2020 Apr;580(7802):245-251. doi: 10.1038/s41586-020-2140-0. Epub 2020 Mar 25.
8
Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.随机试验中 CT 容积筛查降低肺癌死亡率
N Engl J Med. 2020 Feb 6;382(6):503-513. doi: 10.1056/NEJMoa1911793. Epub 2020 Jan 29.
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Lung Cancer Incidence and Mortality with Extended Follow-up in the National Lung Screening Trial.国家肺癌筛查试验中延长随访后的肺癌发病率和死亡率。
J Thorac Oncol. 2019 Oct;14(10):1732-1742. doi: 10.1016/j.jtho.2019.05.044. Epub 2019 Jun 28.
10
Lung cancer mortality reduction by LDCT screening-Results from the randomized German LUSI trial.低剂量计算机断层扫描（LDCT）筛查降低肺癌死亡率-来自德国 LUSI 随机试验的结果。
Int J Cancer. 2020 Mar 15;146(6):1503-1513. doi: 10.1002/ijc.32486. Epub 2019 Jun 20.

Biomarkers in lung cancer screening: the importance of study design.

作者信息

Baldwin David R, Callister Matthew E, Crosbie Philip A, O'Dowd Emma L, Rintoul Robert C, Robbins Hilary A, Steele Robert J C

机构信息

Respiratory Medicine, Nottingham University Hospitals, Nottingham, UK

University of Nottingham, Nottingham, UK.

出版信息

Eur Respir J. 2021 Jan 14;57(1). doi: 10.1183/13993003.04367-2020. Print 2021 Jan.

DOI:10.1183/13993003.04367-2020
PMID:33446580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7968073/
Abstract
摘要