Tang Xuewen, Tang Tingting, Yan Rui, Zhou Yang, Deng Xuan, He Hanqing
Department of Immunization Program, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China.
Department of Immunization Program, Yunnan Provincial Center for Disease Control and Prevention, Kunming, P.R. China.
Hum Vaccin Immunother. 2021 Jun 3;17(6):1686-1692. doi: 10.1080/21645515.2020.1849517. Epub 2021 Jan 15.
: The intention of Chinese people older than age 5 to accept the pertussis vaccination is unknown, which is important for the future design of an effective pertussis vaccination program in China.: We conducted a cross-sectional survey among people older than age 5 in China. A 24-item questionnaire was used to explore the determinants of intention to accept a pertussis vaccination, and for children and adolescents (≦15 years old), their guardian was required to help answer the questionnaire on their behalf. Univariate and multivariate logistic regression was used to analyze the influencing factors of intention.: A total of 3,041 individuals participated in our survey and 3025 completed the questionnaire, among which 1938 (64.07%) reported a positive intention to be vaccinated. A multiple logistic regression analysis revealed that the main positive factors for the intention to accept pertussis vaccination were younger age (Odd ratio [OR] 0.838, < .001), higher educational attainment (OR 1.171, = .002), no hospitalization because of the most recent cough (OR 2.468, < .001), awareness about pertussis (OR 1.958, < .001), and consideration of pertussis vaccination to be safe (OR 1.450, = .026).: There is a relatively high level of intention to receive the pertussis vaccine among people older than age 5 in China. Future pertussis vaccination strategies geared at them should consider focusing on middle-aged and older individuals and those with a low education as well as strengthen the promotion of disease characteristics, vaccine effectiveness, and safety.
5岁以上中国人接受百日咳疫苗接种的意愿尚不清楚,这对中国未来设计有效的百日咳疫苗接种计划很重要。
我们在中国对5岁以上人群进行了一项横断面调查。使用一份包含24个条目的问卷来探究接受百日咳疫苗接种意愿的决定因素,对于儿童和青少年(≤15岁),要求其监护人代他们回答问卷。采用单因素和多因素逻辑回归分析影响因素。
共有3041人参与我们的调查,3025人完成问卷,其中1938人(64.07%)报告有接种疫苗的积极意愿。多因素逻辑回归分析显示,接受百日咳疫苗接种意愿的主要积极因素是年龄较小(比值比[OR]0.838,P<0.001)、教育程度较高(OR 1.171,P=0.002)、近期咳嗽未住院(OR 2.468,P<0.001)、对百日咳的认知(OR 1.958,P<0.001)以及认为百日咳疫苗接种安全(OR 1.450,P=0.026)。
中国5岁以上人群接受百日咳疫苗接种的意愿相对较高。针对他们的未来百日咳疫苗接种策略应考虑关注中年及老年个体和低教育程度人群,并加强对疾病特征、疫苗有效性和安全性的宣传。