Suppr超能文献

强迫症中的对称维度:患病率、严重程度及临床相关性

Symmetry Dimension in Obsessive-Compulsive Disorder: Prevalence, Severity and Clinical Correlates.

作者信息

Vellozo Aline P, Fontenelle Leonardo F, Torresan Ricardo C, Shavitt Roseli G, Ferrão Ygor A, Rosário Maria C, Miguel Euripedes C, Torres Albina R

机构信息

Department of Neurology, Psychology and Psychiatry, Botucatu Medical School, Universidade Estadual Paulista-UNESP, Botucatu 18618-687, Brazil.

Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC 3168, Australia.

出版信息

J Clin Med. 2021 Jan 13;10(2):274. doi: 10.3390/jcm10020274.

Abstract

Obsessive-compulsive disorder (OCD) is a very heterogeneous condition that frequently includes symptoms of the "symmetry dimension" (i.e., obsessions and/or compulsions of symmetry, ordering, repetition, and counting), along with aggressive, sexual/religious, contamination/cleaning, and hoarding dimensions. This cross-sectional study aimed to investigate the prevalence, severity, and demographic and clinical correlates of the symmetry dimension among 1001 outpatients from the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders. The main assessment instruments used were the Dimensional Yale-Brown Obsessive-Compulsive Scale, the Yale-Brown Obsessive-Compulsive Scale, the USP-Sensory Phenomena Scale, the Beck Depression and Anxiety Inventories, the Brown Assessment of Beliefs Scale, and the Structured Clinical Interview for DSM-IV Axis I Disorders. Chi-square tests, Fisher's exact tests, Student's -tests, and Mann-Whitney tests were used in the bivariate analyses to compare patients with and without symptoms of the symmetry dimension. Odds ratios (ORs) with confidence intervals and Cohen's D were also calculated as effect size measures. Finally, a logistic regression was performed to control for confounders. The symmetry dimension was highly prevalent (86.8%) in this large clinical sample and, in the logistic regression, it remained associated with earlier onset of obsessive-compulsive symptoms, insidious onset of compulsions, more severe depressive symptoms, and presence of sensory phenomena. A deeper knowledge about specific OCD dimensions is essential for a better understanding and management of this complex and multifaceted disorder.

摘要

强迫症(OCD)是一种非常异质性的疾病,经常包括“对称维度”的症状(即对称、排序、重复和计数的强迫观念和/或强迫行为),以及攻击性、性/宗教、污染/清洁和囤积维度。这项横断面研究旨在调查巴西强迫症谱系障碍研究联盟的1001名门诊患者中对称维度的患病率、严重程度以及人口统计学和临床相关性。主要使用的评估工具包括维度耶鲁-布朗强迫症量表、耶鲁-布朗强迫症量表、USP感觉现象量表、贝克抑郁和焦虑量表、布朗信念评估量表以及DSM-IV轴I障碍结构化临床访谈。在双变量分析中使用卡方检验、费舍尔精确检验、学生t检验和曼-惠特尼检验来比较有和没有对称维度症状的患者。还计算了带有置信区间的优势比(OR)和科恩d值作为效应量指标。最后,进行逻辑回归以控制混杂因素。在这个大型临床样本中,对称维度非常普遍(86.8%),并且在逻辑回归中,它仍然与强迫症症状的更早发作、强迫行为的隐匿性发作、更严重的抑郁症状以及感觉现象的存在相关。深入了解特定的强迫症维度对于更好地理解和管理这种复杂多面的疾病至关重要。

相似文献

2
Clinical features of obsessive-compulsive disorder with hoarding symptoms: a multicenter study.
J Psychiatr Res. 2012 Jun;46(6):724-32. doi: 10.1016/j.jpsychires.2012.03.005. Epub 2012 Mar 31.
4
Body dysmorphic disorder in patients with obsessive-compulsive disorder: prevalence and clinical correlates.
Depress Anxiety. 2012 Nov;29(11):966-75. doi: 10.1002/da.21980. Epub 2012 Jul 19.
6
Symptom dimensions, clinical course and comorbidity in men and women with obsessive-compulsive disorder.
Psychiatry Res. 2013 Sep 30;209(2):186-95. doi: 10.1016/j.psychres.2012.12.006. Epub 2013 Jan 5.
7
Clinical features of pure obsessive-compulsive disorder.
Compr Psychiatry. 2013 Oct;54(7):1042-52. doi: 10.1016/j.comppsych.2013.04.013. Epub 2013 Jun 6.
8
The suicidality continuum in a large sample of obsessive-compulsive disorder (OCD) patients.
Eur Psychiatry. 2016 Oct;38:1-7. doi: 10.1016/j.eurpsy.2016.05.003. Epub 2016 Sep 6.

引用本文的文献

1
Harm Avoidance and Incompleteness as Motivational Dimensions of OCD: Associations with Clinical and Demographic Traits.
Cognit Ther Res. 2025 Aug;49(4):795-806. doi: 10.1007/s10608-024-10561-2. Epub 2025 Jan 25.
4
The Relationship between OCD and Depression in Adults: A Review of Recent Findings.
Curr Psychiatry Rep. 2025 Apr;27(4):187-198. doi: 10.1007/s11920-025-01589-6. Epub 2025 Feb 21.
5
Sensory phenomena in children with Tourette syndrome or autism spectrum disorder.
Front Psychiatry. 2024 Apr 2;15:1338234. doi: 10.3389/fpsyt.2024.1338234. eCollection 2024.
6
Study on symptom dimensions and clinical characteristics in patients with obsessive-compulsive disorder.
Rev Assoc Med Bras (1992). 2024 Mar 15;70(1):e20230676. doi: 10.1590/1806-9282.20230676. eCollection 2024.
7
Associations Between Suicidality and Interoception in Obsessive-Compulsive Disorder.
J Obsessive Compuls Relat Disord. 2023 Oct;39. doi: 10.1016/j.jocrd.2023.100844. Epub 2023 Oct 4.
8
Neurogenetics of Dynamic Connectivity Patterns Associated With Obsessive-Compulsive Symptoms in Healthy Children.
Biol Psychiatry Glob Open Sci. 2021 Nov 27;2(4):411-420. doi: 10.1016/j.bpsgos.2021.11.009. eCollection 2022 Oct.
10
Genetics of obsessive-compulsive disorder.
Psychol Med. 2021 Oct;51(13):2247-2259. doi: 10.1017/S0033291721001744. Epub 2021 May 25.

本文引用的文献

1
Diagnostic Issues in Early-Onset Obsessive-Compulsive Disorder and their Treatment Implications.
Curr Neuropharmacol. 2019;17(8):672-680. doi: 10.2174/1570159X16666180426151746.
2
Relationships between neuropsychological variables and factor-analysed symptom dimensions in obsessive compulsive disorder.
Psychiatry Res. 2017 Mar;249:58-64. doi: 10.1016/j.psychres.2016.12.044. Epub 2016 Dec 29.
3
Exploring yale-brown obsessive-compulsive scale symptom structure in Iranian OCD patients using item-based factor analysis.
Psychiatry Res. 2016 Nov 30;245:416-422. doi: 10.1016/j.psychres.2016.08.028. Epub 2016 Aug 8.
4
Association of GRIN2B gene polymorphism and Obsessive Compulsive disorder and symptom dimensions: A pilot study.
Psychiatry Res. 2016 Sep 30;243:152-5. doi: 10.1016/j.psychres.2016.06.027. Epub 2016 Jun 25.
6
An empirical investigation of incompleteness in a large clinical sample of obsessive compulsive disorder.
J Anxiety Disord. 2016 Aug;42:45-51. doi: 10.1016/j.janxdis.2016.05.005. Epub 2016 May 13.
7
Incompleteness and not just right experiences in the explanation of Obsessive-Compulsive Disorder.
Psychiatry Res. 2016 Feb 28;236:1-8. doi: 10.1016/j.psychres.2016.01.012. Epub 2016 Jan 7.
8
Symmetry symptoms in obsessive-compulsive disorder: clinical and genetic correlates.
Braz J Psychiatry. 2016 Mar;38(1):17-23. doi: 10.1590/1516-4446-2014-1619. Epub 2015 Aug 18.
9
Is late-onset OCD a distinct phenotype? Findings from a comparative analysis of "age at onset" groups.
CNS Spectr. 2015 Oct;20(5):508-14. doi: 10.1017/S1092852914000777. Epub 2015 Jul 20.
10
Visual, tactile, and auditory "not just right" experiences: associations with obsessive-compulsive symptoms and perfectionism.
Behav Ther. 2014 Sep;45(5):678-89. doi: 10.1016/j.beth.2014.03.008. Epub 2014 Mar 27.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验