Vellozo Aline P, Fontenelle Leonardo F, Torresan Ricardo C, Shavitt Roseli G, Ferrão Ygor A, Rosário Maria C, Miguel Euripedes C, Torres Albina R
Department of Neurology, Psychology and Psychiatry, Botucatu Medical School, Universidade Estadual Paulista-UNESP, Botucatu 18618-687, Brazil.
Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC 3168, Australia.
J Clin Med. 2021 Jan 13;10(2):274. doi: 10.3390/jcm10020274.
Obsessive-compulsive disorder (OCD) is a very heterogeneous condition that frequently includes symptoms of the "symmetry dimension" (i.e., obsessions and/or compulsions of symmetry, ordering, repetition, and counting), along with aggressive, sexual/religious, contamination/cleaning, and hoarding dimensions. This cross-sectional study aimed to investigate the prevalence, severity, and demographic and clinical correlates of the symmetry dimension among 1001 outpatients from the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders. The main assessment instruments used were the Dimensional Yale-Brown Obsessive-Compulsive Scale, the Yale-Brown Obsessive-Compulsive Scale, the USP-Sensory Phenomena Scale, the Beck Depression and Anxiety Inventories, the Brown Assessment of Beliefs Scale, and the Structured Clinical Interview for DSM-IV Axis I Disorders. Chi-square tests, Fisher's exact tests, Student's -tests, and Mann-Whitney tests were used in the bivariate analyses to compare patients with and without symptoms of the symmetry dimension. Odds ratios (ORs) with confidence intervals and Cohen's D were also calculated as effect size measures. Finally, a logistic regression was performed to control for confounders. The symmetry dimension was highly prevalent (86.8%) in this large clinical sample and, in the logistic regression, it remained associated with earlier onset of obsessive-compulsive symptoms, insidious onset of compulsions, more severe depressive symptoms, and presence of sensory phenomena. A deeper knowledge about specific OCD dimensions is essential for a better understanding and management of this complex and multifaceted disorder.
强迫症（OCD）是一种非常异质性的疾病，经常包括“对称维度”的症状（即对称、排序、重复和计数的强迫观念和/或强迫行为），以及攻击性、性/宗教、污染/清洁和囤积维度。这项横断面研究旨在调查巴西强迫症谱系障碍研究联盟的1001名门诊患者中对称维度的患病率、严重程度以及人口统计学和临床相关性。主要使用的评估工具包括维度耶鲁-布朗强迫症量表、耶鲁-布朗强迫症量表、USP感觉现象量表、贝克抑郁和焦虑量表、布朗信念评估量表以及DSM-IV轴I障碍结构化临床访谈。在双变量分析中使用卡方检验、费舍尔精确检验、学生t检验和曼-惠特尼检验来比较有和没有对称维度症状的患者。还计算了带有置信区间的优势比（OR）和科恩d值作为效应量指标。最后，进行逻辑回归以控制混杂因素。在这个大型临床样本中，对称维度非常普遍（86.8%），并且在逻辑回归中，它仍然与强迫症症状的更早发作、强迫行为的隐匿性发作、更严重的抑郁症状以及感觉现象的存在相关。深入了解特定的强迫症维度对于更好地理解和管理这种复杂多面的疾病至关重要。
