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强迫症患者症状维度及临床特征研究。

Study on symptom dimensions and clinical characteristics in patients with obsessive-compulsive disorder.

机构信息

Capital Medical University, Beijing Anding Hospital, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, Beijing Key Laboratory of Mental Disorders - Beijing, China.

Capital Medical University, Advanced Innovation Center for Human Brain Protection - Beijing, China.

出版信息

Rev Assoc Med Bras (1992). 2024 Mar 15;70(1):e20230676. doi: 10.1590/1806-9282.20230676. eCollection 2024.

DOI:10.1590/1806-9282.20230676
PMID:38511751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10941875/
Abstract

BACKGROUND AND OBJECTIVE

The aim of this study was to explore the symptom dimensions and clinical characteristics of obsessive-compulsive disorder in the context of Chinese culture.

METHODS

In this cross-sectional study, the severity of obsessive-compulsive symptoms, the distribution of symptoms, and symptom scores of 263 patients with obsessive-compulsive disorder were assessed using the Yale-Brown Obsessive-Compulsive Scale and Yale-Brown Obsessive-Compulsive Inventory Symptoms Checklist. System cluster analysis and Pearson analysis were performed to explore the relationships between the main clinical characteristics and symptom dimensions.

RESULTS

Cluster analysis identified four symptom dimensions of obsessive-compulsive disorder: (1) symmetry precision; (2) contamination cleaning; (3) aggression examination; and (4) taboo thinking. The symmetry precision dimension showed an association with years of education. The compulsive score, total Yale-Brown Obsessive Compulsive Scale score, contamination cleaning dimension, and aggression examination dimension had significant relationships. Age, age at onset, obsessive score, and compulsive score had a significant correlation with the taboo-thinking dimension.

CONCLUSION

The symptom dimensions of obsessive-compulsive disorder in China are similar to those in other regions. Each of the four symptom dimensions had distinct clinical characteristics.

摘要

背景与目的

本研究旨在探讨中国文化背景下强迫症的症状维度和临床特征。

方法

在这项横断面研究中,使用耶鲁-布朗强迫症量表和耶鲁-布朗强迫症症状清单评估了 263 例强迫症患者的强迫症症状严重程度、症状分布和症状评分。采用系统聚类分析和 Pearson 分析探讨主要临床特征与症状维度之间的关系。

结果

聚类分析确定了强迫症的四个症状维度:(1)对称精确;(2)污染清洁;(3)攻击检查;和(4)禁忌思维。对称精确维度与受教育年限有关。强迫症评分、耶鲁-布朗强迫症量表总分、污染清洁维度和攻击检查维度之间存在显著相关性。年龄、发病年龄、强迫评分与禁忌思维维度有显著相关性。

结论

中国强迫症的症状维度与其他地区相似。四个症状维度中的每一个都有独特的临床特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0cf/10941875/8bc368ae1516/1806-9282-ramb-70-1-e20230676-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0cf/10941875/8bc368ae1516/1806-9282-ramb-70-1-e20230676-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0cf/10941875/8bc368ae1516/1806-9282-ramb-70-1-e20230676-gf01.jpg

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Deep Brain Stimulation for Obsessive-Compulsive Disorder: Real World Experience Post-FDA-Humanitarian Use Device Approval.用于强迫症的深部脑刺激:FDA批准人道主义使用设备后的真实世界经验
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Compassion-Focused Group Therapy for Treatment-Resistant OCD: Initial Evaluation Using a Multiple Baseline Design.针对难治性强迫症的以同情为中心的团体治疗:采用多基线设计的初步评估
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强迫症中的对称维度:患病率、严重程度及临床相关性
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Efficacy and clinical predictors of response to rTMS treatment in pharmacoresistant obsessive-compulsive disorder (OCD): a retrospective study.药物难治性强迫症(OCD)患者重复经颅磁刺激(rTMS)治疗的疗效及临床预测因子:一项回顾性研究。
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