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环状肉芽肿亚型:超声表现与临床病理相关性。

Granuloma annulare subtypes: sonographic features and clinicopathological correlation.

机构信息

Dermatology Department, Clinica Universidad de Navarra, Pamplona, Spain.

Cutaneous Ultrasound Unit, Dermatology Department, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain.

出版信息

J Ultrasound. 2022 Jun;25(2):289-295. doi: 10.1007/s40477-020-00532-0. Epub 2021 Jan 16.

DOI:10.1007/s40477-020-00532-0
PMID:33453055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9148323/
Abstract

PURPOSE

Diagnosis of granuloma annulare (GA) is based on the clinical and histopathological findings. However, only sporadic case reports of subcutaneous GA sonography have been published to date. The objective of this study was to evaluate the ultrasonographic patterns of the different clinical variants of GA: localized, generalized, subcutaneous, and perforating.

METHODS

In this retrospective observational study, we analyzed and correlated the clinical, histopathological, and sonographic features of 15 patients diagnosed with GA.

RESULTS

We included 8 women and 7 men with a mean age of 48.4 years (8-77 years). We found three different sonographic patterns depending on the clinical variant of GA: poorly defined hypoechoic band including the dermis (dermal pattern), irregularly shaped hypoechoic hypodermal lumps (hypodermal pattern), and ill-defined hypoechoic dermal and subcutaneous lesions (mixed pattern). Five cases showed increased blood flow signal on Doppler interrogation.

CONCLUSION

Although our findings are broadly consistent with the previous reports of subcutaneous GA, the sonographic features in localized, generalized, and perforating GA have not been previously reported.

摘要

目的

环状肉芽肿(GA)的诊断基于临床和组织病理学发现。然而,迄今为止,仅发表了少数关于皮下 GA 超声的病例报告。本研究的目的是评估不同临床变异型 GA 的超声模式:局限性、全身性、皮下型和穿凿性。

方法

在这项回顾性观察研究中,我们分析和关联了 15 例诊断为 GA 的患者的临床、组织病理学和超声特征。

结果

我们纳入了 8 名女性和 7 名男性,平均年龄为 48.4 岁(8-77 岁)。根据 GA 的临床变异型,我们发现了三种不同的超声模式:包括真皮的界限不清的低回声带(真皮模式)、不规则形状的低回声皮下肿块(皮下模式)和界限不清的低回声真皮和皮下病变(混合模式)。5 例在多普勒检查时显示血流信号增加。

结论

尽管我们的发现与先前关于皮下 GA 的报告基本一致,但局限性、全身性和穿凿性 GA 的超声特征以前尚未报道过。

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A bump: what to do next? Ultrasound imaging of superficial soft-tissue palpable lesions.一个肿块:下一步该怎么办?浅表软组织可触及病变的超声成像。
J Ultrasound. 2020 Sep;23(3):287-300. doi: 10.1007/s40477-019-00415-z. Epub 2019 Nov 30.
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Cutaneous ultrasound and its utility in pediatric dermatology. Part I: Lumps, bumps, and inflammatory conditions.皮肤超声及其在儿科皮肤病学中的应用。第一部分:肿块、隆起及炎症性疾病。
Pediatr Dermatol. 2020 Jan;37(1):29-39. doi: 10.1111/pde.14033. Epub 2019 Nov 19.
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Skin cancer: findings and role of high-resolution ultrasound.皮肤癌:高分辨率超声的研究结果及作用
J Ultrasound. 2019 Dec;22(4):423-431. doi: 10.1007/s40477-019-00379-0. Epub 2019 May 8.
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Utility of a gel stand-off pad in the detection of Doppler signal on focal nodular lesions of the skin.凝胶隔离垫在皮肤局灶性结节病变多普勒信号检测中的应用。
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Classification and ultrasound findings of vascular anomalies in pediatric age: the essential.儿童期血管异常的分类及超声表现:要点
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Comment on "Usefulness of ultrasonography in the diagnosis of subcutaneous granuloma annulare".关于《超声检查在诊断皮下环状肉芽肿中的应用价值》的评论
Pediatr Dermatol. 2018 Nov;35(6):875-876. doi: 10.1111/pde.13615.
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Ultrasonography of benign vulvar lesions.良性外阴病变的超声检查
Ultrasonography. 2018 Oct;37(4):355-360. doi: 10.14366/usg.18001. Epub 2018 Feb 13.
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Pediatr Dermatol. 2018 May;35(3):e200-e201. doi: 10.1111/pde.13470. Epub 2018 Mar 24.
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J Ultrasound Med. 2016 Nov;35(11):2305-2309. doi: 10.7863/ultra.15.10068. Epub 2016 Sep 14.
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J Am Acad Dermatol. 2016 Sep;75(3):467-479. doi: 10.1016/j.jaad.2015.03.055.