McKenna Ciara G, Vaughan Ted J
Biomechanics Research Centre (BioMEC), Biomedical Engineering, School of Engineering, College of Science and Engineering, National University of Ireland Galway, Galway, Ireland.
Biomechanics Research Centre (BioMEC), Biomedical Engineering, School of Engineering, College of Science and Engineering, National University of Ireland Galway, Galway, Ireland.
J Mech Behav Biomed Mater. 2021 Mar;115:104305. doi: 10.1016/j.jmbbm.2020.104305. Epub 2021 Jan 7.
Self-expanding covered braided stents are routinely used across a diverse range of clinical applications, but few computational studies have attempted to replicate their complex behaviour. In this study, a computational framework was developed to predict the functional performance of bare and covered self-expanding wire braided stents, with a systematic evaluation on the effect of various braid and cover parameters presented. Simulated radial force and kink deformation tests show good agreement to experimental data for covered braided stents across a range of braid angles and cover thicknesses. Our results demonstrate that braid angle is a key governing parameter that dictates the radial and kink performance of both bare-metal and covered wire braided stents. It was also demonstrated that addition of a polymeric cover to a wire braided stent causes a stiffer radial response across all braid angles, particularly when thicker and/or stiffer covering systems were considered. This study represents the first experimentally-validated computational model for covered wire braided stent systems and has excellent potential to be used in future design of these devices for a range of applications.
自膨胀带膜编织支架在各种临床应用中都有常规使用，但很少有计算研究试图复制其复杂行为。在本研究中，开发了一个计算框架来预测裸支架和带膜自膨胀金属丝编织支架的功能性能，并对各种编织和覆膜参数的影响进行了系统评估。模拟的径向力和扭结变形测试表明，对于不同编织角度和覆膜厚度的带膜编织支架，其结果与实验数据吻合良好。我们的结果表明，编织角度是决定裸金属和带膜金属丝编织支架径向和扭结性能的关键控制参数。还表明，在金属丝编织支架上添加聚合物覆膜会导致在所有编织角度下产生更硬的径向响应，特别是当考虑更厚和/或更硬的覆膜系统时。本研究代表了首个经过实验验证的带膜金属丝编织支架系统计算模型，在未来这些装置的一系列应用设计中具有巨大的应用潜力。
