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七鳃鳗脊髓中的一类新型小抑制性中间神经元。

A new class of small inhibitory interneurones in the lamprey spinal cord.

作者信息

Buchanan J T, Grillner S

机构信息

Nobel Institute for Neurophysiology, Karolinska Institute, Stockholm, Sweden.

出版信息

Brain Res. 1988 Jan 12;438(1-2):404-7. doi: 10.1016/0006-8993(88)91373-x.

DOI:10.1016/0006-8993(88)91373-x
PMID:3345449
Abstract

Paired intracellular recordings of interneurones and motoneurones have been performed in the lamprey spinal cord in vitro. One new type of small interneurone (10-15 microns in diameter) which produces monosynaptic inhibitory postsynaptic potentials (IPSPs) in motoneurones is described. The IPSP is strychnine-sensitive and thus presumably glycinergic. This type of interneurone undergoes rhythmical membrane potential oscillations during fictive locomotion and intracellular stimulation can have a profound effect on the burst generation occurring during fictive locomotion.

摘要

已在体外对七鳃鳗脊髓中的中间神经元和运动神经元进行了配对细胞内记录。本文描述了一种新型的小中间神经元(直径为10 - 15微米),它在运动神经元中产生单突触抑制性突触后电位(IPSPs)。该IPSP对士的宁敏感,因此推测为甘氨酸能。在虚拟运动期间,这种类型的中间神经元会经历节律性膜电位振荡,并且细胞内刺激可对虚拟运动期间发生的爆发产生深远影响。

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