对活跃的溶藻弧菌噬菌体的全基因组分析。

Complete genome analysis of an active prophage of Vibrio alginolyticus.

机构信息

Key Laboratory of Marine Biotechnology, School of Marine Sciences, Ningbo University, Ningbo, 315211, China.

Beijing University of Chemical Technology, Beijing, 100029, China.

出版信息

Arch Virol. 2021 Mar;166(3):891-896. doi: 10.1007/s00705-020-04941-8. Epub 2021 Jan 16.

DOI:10.1007/s00705-020-04941-8

PMID:33454862

Abstract

An active prophage, Vibrio phage ValM-yong1, was isolated from pathogenic Vibrio alginolyticus by mitomycin C induction. This phage is a member of the family Myoviridae and contains a head approximately 90 nm in diameter and a retractable tail approximately 250 nm in length. The genome of the phage is 33,851 bp in length with a G+C content of 45.6%. The noteworthy features of Vibrio phage ValM-yong1 are its flower-like head and genomic mosaicism. Here, we focus on presenting the genomic characterization of the virus.

摘要

一种活性噬菌体，即鳗弧菌噬菌体 ValM-yong1，通过丝裂霉素 C 诱导从致病性鳗弧菌中分离出来。该噬菌体属于肌尾噬菌体科，其头部直径约为 90nm，可伸缩的尾部长度约为 250nm。噬菌体基因组全长 33851bp，GC 含量为 45.6%。鳗弧菌噬菌体 ValM-yong1 的显著特征是其花瓣状头部和基因组镶嵌性。在这里，我们主要介绍该病毒的基因组特征。