Spinal Cord and Brain Injury Research Center, Department of Physiology, University of Kentucky Medical School, Lexington, KY, USA.
Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Neuroinformatics. 2022 Jan;20(1):3-6. doi: 10.1007/s12021-020-09498-0. Epub 2021 Jan 16.
There are few pharmacological therapeutics available for spinal cord injury despite years of preclinical and clinical research. This brief editorial discusses some of the shortcomings of translational research efforts. In addition, we comment on our previous experiences with data curation and highlight evolving efforts by the spinal cord injury research community to improve prospects for future therapeutic development, especially pertaining to preclinical data sharing through the Open Data Commons for Spinal Cord Injury (ODC-SCI).
尽管经过了多年的临床前和临床研究,但可用于治疗脊髓损伤的药物治疗方法却寥寥无几。这篇简短的社论讨论了转化研究工作的一些缺点。此外,我们还对我们之前的数据管理经验进行了评论,并强调了脊髓损伤研究界为改善未来治疗开发前景而正在进行的努力,特别是通过开放脊髓损伤数据共享 Commons(ODC-SCI)来共享临床前数据。