Frank Derek S, Aldoukhi Ali H, Roberts William W, Ghani Khurshid R, Matzger Adam J
Department of Chemistry and the Macromolecular Science & Engineering Program, University of Michigan, 930 North University, Ann Arbor, Michigan 48109, United States.
Division of Endourology, Department of Urology, University of Michigan, 1500 East Medical Central Drive, SPC 5330, Ann Arbor, Michigan 48109, United States.
ACS Biomater Sci Eng. 2019 Oct 14;5(10):4970-4975. doi: 10.1021/acsbiomaterials.9b01130. Epub 2019 Sep 16.
Despite the widespread use of laser lithotripsy to fragment kidney stones in vivo, there is a lack of robust artificial stone models to replicate the behavior of human stones during lithotripsy procedures. This need for accurate stone models is particularly important as novel laser technologies are introduced in the field of lithotripsy. In this work, we present a method to prepare composite materials that replicate the properties of human kidney stones during laser lithotripsy. Their behavior is understood through the lens of near-IR spectroscopy and helps to elucidate the mechanism of laser lithotripsy in kidney stone materials.
尽管激光碎石术在体内破碎肾结石方面得到了广泛应用，但缺乏强大的人工结石模型来复制人类结石在碎石过程中的行为。随着新型激光技术引入碎石领域，对精确结石模型的需求尤为重要。在这项工作中，我们提出了一种制备复合材料的方法，该材料在激光碎石过程中能复制人类肾结石的特性。通过近红外光谱的视角来理解它们的行为，这有助于阐明肾结石材料中激光碎石的机制。
