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用于生物传感器应用的可贴皮电极:综述。

Skin-Patchable Electrodes for Biosensor Applications: A Review.

机构信息

Center for Electrochemical Science and Materials, Department of Chemistry, KLE Institute of Technology, Hubballi 580 030, Karnataka, India.

Department of Chemistry, Bilkent University, Cankaya, Ankara 06008, Turkey.

出版信息

ACS Biomater Sci Eng. 2020 Apr 13;6(4):1823-1835. doi: 10.1021/acsbiomaterials.9b01659. Epub 2020 Mar 27.

Abstract

Health care monitoring is an extremely important aspect of human life that can be accomplished using wearable skin-patchable sensors. Upon interfacing with the skin or epidermal surface of the body, the sensing patches can monitor the movements of human parts such joints, legs, and fingers as well as tiny vibrations caused by respiration, blood flow, and heart beat. Wearable skin patches have shown improved promise in monitoring the body temperature and fever in addition to quick measurement of blood pressure and pulse rate along with breathing rate. Sensors can also analyze the sweat contents when in contact with the skin as well as other analytes such as diabetes-based volatile organic compounds (VOCs) and organophosphate nerve stimulating agents. Hence, the sensors can be of immense help in the early prediction of malfunctions of the body organs such as heart and lungs, leading to timely and effective treatment. This review covers different important aspects of skin-patchable sensors including mechanical strength and flexibility, sensitivity, transparency, self-healing, self-cleaning, and self-powering ability as well as their latest applications in medical technology.

摘要

医疗保健监测是人类生活中极其重要的一个方面,可以使用可穿戴的皮肤贴合传感器来实现。这些感应贴片与身体的皮肤或表皮表面相连接,能够监测关节、腿部和手指等人体部位的运动以及呼吸、血流和心跳引起的微小振动。可穿戴的皮肤贴片在监测体温和发烧方面显示出了更大的潜力,除此之外,还可以快速测量血压和脉搏以及呼吸频率。传感器还可以分析与皮肤接触时的汗液含量以及其他分析物,如基于糖尿病的挥发性有机化合物(VOCs)和有机磷神经刺激剂。因此,这些传感器可以极大地帮助早期预测心脏和肺部等身体器官的故障,从而进行及时有效的治疗。本综述涵盖了皮肤贴合传感器的不同重要方面,包括机械强度和灵活性、灵敏度、透明度、自修复、自清洁和自供电能力,以及它们在医疗技术中的最新应用。

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