Takao Miki, Oishi Akio, Shimizu Toshimasa, Kuwatsuka Yutaka, Kitaoka Takashi
Department of Ophthalmology and Visual Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Department of Ophthalmology, National Hospital Organization Nagasaki Medical Center, Omura, Japan.
Am J Ophthalmol Case Rep. 2023 Nov 4;32:101955. doi: 10.1016/j.ajoc.2023.101955. eCollection 2023 Dec.
We report a case of systemic sclerosis-associated paracentral acute middle maculopathy (PAMM) in a young woman who subsequently developed branch retinal artery occlusion.
A 22-year-old woman presented with a paracentral scotoma. Optical coherence tomography (OCT) revealed bilateral paracentral acute middle maculopathy. Upon systemic examination, she was diagnosed with systemic sclerosis (SSc). She subsequently developed branch retinal artery occlusion despite vasodilator medications. After the prescription of aspirin, she did not experience a new event for one year.
This case illustrates that SSc may affect the retinal vascular system and vision and cause PAMM. The optimal prophylaxis for patients with recurrent retinal events should be investigated in future studies.
我们报告一例年轻女性系统性硬化症相关的中心旁急性黄斑中病变（PAMM），该患者随后发生了视网膜分支动脉阻塞。
一名22岁女性出现中心旁暗点。光学相干断层扫描（OCT）显示双侧中心旁急性黄斑中病变。经全身检查，她被诊断为系统性硬化症（SSc）。尽管使用了血管扩张药物，她随后仍发生了视网膜分支动脉阻塞。服用阿司匹林后，她一年未出现新的事件。
该病例表明SSc可能影响视网膜血管系统和视力，并导致PAMM。未来的研究应探讨复发性视网膜事件患者的最佳预防措施。
