Department of Medical Physics, Royal Surrey County Hospital, Guildford, UK.
Radiother Oncol. 2013 Jul;108(1):78-85. doi: 10.1016/j.radonc.2013.05.027. Epub 2013 Jun 12.
To develop a methodology for the use of a commercial detector array in dosimetry audits of rotational radiotherapy.
The methodology was developed as part of the development of a national audit of rotational radiotherapy. Ten cancer centres were asked to create a rotational radiotherapy treatment plan for a three-dimensional treatment-planning-system (3DTPS) test and audited. Phantom measurements using a commercial 2D ionisation chamber (IC) array were compared with measurements using 0.125 cm(3) IC, Gafchromic film and alanine pellets in the same plane. Relative and absolute gamma index (γ) comparisons were made for Gafchromic film and 2D-Array planes, respectively.
Comparisons between individual detectors within the 2D-Array against the corresponding IC and alanine measurement showed a statistically significant concordance correlation coefficient (both ρc>0.998, p<0.001) with mean difference of -1.1 ± 1.1% and -0.8 ± 1.1%, respectively, in a high dose PTV. In the γ comparison between the 2D-Array and film it was that the 2D-Array was more likely to fail planes where there was a dose discrepancy due to the absolute analysis performed.
It has been found that using a commercial detector array for a dosimetry audit of rotational radiotherapy is suitable in place of standard systems of dosimetry.
开发一种使用商业探测器阵列进行旋转放射治疗剂量学审核的方法。
该方法是作为旋转放射治疗国家审核开发的一部分而开发的。要求十个癌症中心为三维治疗计划系统(3DTPS)测试创建旋转放射治疗计划,并进行审核。使用商业二维电离室(IC)阵列进行的体模测量与同一平面上使用 0.125cm³IC、Gafchromic 胶片和丙氨酸小球进行的测量进行了比较。分别对 Gafchromic 胶片和 2D 阵列平面进行相对和绝对伽马指数(γ)比较。
2D 阵列中各个探测器与相应的 IC 和丙氨酸测量之间的比较显示出统计学上显著的一致性相关系数(均 ρc>0.998,p<0.001),高剂量 PTV 中的平均差异分别为-1.1±1.1%和-0.8±1.1%。在 2D 阵列和胶片之间的γ比较中,由于进行了绝对分析,2D 阵列更有可能导致剂量差异的平面失败。
已经发现,使用商业探测器阵列进行旋转放射治疗的剂量学审核适合替代标准的剂量学系统。