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儿童SARS-CoV-2感染所致嗅觉丧失的嗅球磁共振成像

Olfactory bulb magnetic resonance imaging in SARS-CoV-2-induced anosmia in pediatric cases.

作者信息

Hatipoglu Nevin, Yazici Zahide Mine, Palabiyik Figen, Gulustan Filiz, Sayin Ibrahim

机构信息

Department of Pediatric Infection, Health Science University, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Department of Otolaryngology, Health Science University, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

出版信息

Int J Pediatr Otorhinolaryngol. 2020 Dec;139:110469. doi: 10.1016/j.ijporl.2020.110469. Epub 2020 Oct 24.

Abstract

In this paper, we report three cases of pediatric patients with COVID-19 infection who presented with different symptoms and also anosmia and/or ageusia. The common feature of these 3 patients is that the smell and / or taste disorder developed without nasal symptoms such as nasal congestion, nasal obstruction or rhinorrhea. Although 40% of anosmies contains viral etiologies, COVID- 19 differs from other viral anosmies by the lack of nasal congestion and runny nose. Coronaviruses could invade the brain via the cribriform plate close to the olfactory bulb and the olfactory epithelium. We may expect some structural changes in the olfactory bulb so we evaluated our patient with cranial imaging.

摘要

在本文中,我们报告了3例感染新型冠状病毒肺炎(COVID-19)的儿科患者,他们表现出不同症状,还伴有嗅觉丧失和/或味觉丧失。这3例患者的共同特征是,嗅觉和/或味觉障碍在没有鼻塞、鼻阻塞或流涕等鼻部症状的情况下出现。虽然40%的嗅觉丧失病例存在病毒病因,但COVID-19与其他病毒性嗅觉丧失不同,不存在鼻塞和流涕症状。冠状病毒可通过靠近嗅球和嗅上皮的筛板侵入大脑。我们预计嗅球会出现一些结构变化,因此我们对患者进行了头颅成像评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fc1/7584919/2345b9919c99/gr1_lrg.jpg

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