Mizan- Tepi University, Mizan-Aman, Ethiopia.
Inquiry. 2023 Jan-Dec;60:469580231166794. doi: 10.1177/00469580231166794.
Coronavirus disease 2019 (COVID-19) is caused by a severe acute respiratory syndrome coronavirus (SARS-CoV-2) and became pandemic after emerging in Wuhan, China, in December 2019. We aimed to investigate the prevalence, clinical characteristics, and risk factors for SARS-CoV-2 infections in districts of southwest Ethiopia. A study was conducted on COVID-19 surveillance data in the diagnostic center of the southwest district of Ethiopia from July 1, 2020, to February 30, 2021. A total of 10 618 nasopharyngeal specimens were tested for SARS-COV-2 using the detection of unique sequences of virus RNA by reverse transcriptase PCR. Data were entered into Epidata version 3.1 and analyzed using SPSS version 25. Logistic regression was used to determine the relationship between COVID-19 and risk factors, with a significance level of = 0.05. A total of 10 618 individuals were tested for SARS-CoV-2. Of these, 419 (3.9%) patients tested positive for SARS-CoV-2. Among a total of 419 patients who tested positive for SARS-CoV-2, 80.2% were asymptomatic, 264 (63.0%) were males, and 233 (55.6%) were aged 19 to 35 years. Comorbidity was present in 37 (8.8%). The risk of getting SARS-CoV-2 infections was increased with male sex (AOR = 1.248; 95% CI: 1.007, 1.547), health workers (AOR = 3.187; 95% CI: 1.960, 5.182), prisoners (AOR = 2.118; 95% CI: 1.104, 4.062), and comorbid conditions (AOR = 2.972; 95% CI: 1.649, 5.358), such as diabetes (AOR = 4.765; 95% CI: 1.977-11.485) and other respiratory problems (AOR = 3.267; 95% CI: 1.146-9.317). Despite the fact that overall laboratories confirmed prevalence of SARS-CoV-2 infections in the study area was low and dynamic, it was spread to all zones of the study area. This highlights the importance of implementing the most effective public health strategies to prevent the further spread and reduce the burden of SARS-CoV-2 infections.
新型冠状病毒病（COVID-19）由严重急性呼吸系统综合症冠状病毒（SARS-CoV-2）引起，于 2019 年 12 月在中国武汉出现后成为大流行。我们旨在研究埃塞俄比亚西南部地区 SARS-CoV-2 感染的流行率、临床特征和危险因素。这项研究于 2020 年 7 月 1 日至 2021 年 2 月 30 日期间，在埃塞俄比亚西南部地区诊断中心对 COVID-19 监测数据进行了调查。使用逆转录酶聚合酶链反应检测病毒 RNA 的独特序列，对总共 10618 个鼻咽标本进行了 SARS-CoV-2 检测。数据输入到 Epidata 版本 3.1 中，并使用 SPSS 版本 25 进行分析。逻辑回归用于确定 COVID-19 与危险因素之间的关系，显著性水平为 = 0.05。总共对 10618 人进行了 SARS-CoV-2 检测。其中，419 名（3.9%）患者 SARS-CoV-2 检测呈阳性。在总共 419 名 SARS-CoV-2 检测呈阳性的患者中，80.2%为无症状，264 名（63.0%）为男性，233 名（55.6%）年龄在 19 至 35 岁之间。有 37 名（8.8%）患者合并症。男性（AOR=1.248；95%CI：1.007，1.547）、卫生工作者（AOR=3.187；95%CI：1.960，5.182）、囚犯（AOR=2.118；95%CI：1.104，4.062）和合并症（AOR=2.972；95%CI：1.649，5.358），如糖尿病（AOR=4.765；95%CI：1.977-11.485）和其他呼吸系统问题（AOR=3.267；95%CI：1.146-9.317），感染 SARS-CoV-2 的风险增加。尽管研究区域实验室确诊的 SARS-CoV-2 感染总体流行率较低且具有动态性，但它已传播到研究区域的所有区域。这凸显了实施最有效的公共卫生策略以防止进一步传播和减轻 SARS-CoV-2 感染负担的重要性。
