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非酒精性脂肪性肝病相关性肝硬化在生育期女性中发病率上升,是妊娠相关肝硬化的最常见病因。

NAFLD Cirrhosis Is Rising Among Childbearing Women and Is the Most Common Cause of Cirrhosis in Pregnancy.

机构信息

Division of Gastroenterology and Hepatology, University of California, San Francisco, San Francisco, California.

ICES, Queen's University, Kingston, Ontario, Canada.

出版信息

Clin Gastroenterol Hepatol. 2022 Feb;20(2):e315-e318. doi: 10.1016/j.cgh.2021.01.022. Epub 2021 Jan 16.

Abstract

Rates of pregnancies affected by nonalcoholic fatty liver disease (NAFLD) in the United States have nearly tripled in the last decade and NAFLD confers increased perinatal risks, such as hypertensive complications, postpartum hemorrhage, and preterm birth. Rates of cirrhosis in pregnancy are also rising, although estimates specific to NAFLD cirrhosis are lacking. Whether NAFLD cirrhosis confers differential perinatal risks than other causes of cirrhosis in pregnancy is also unknown.

摘要

美国受非酒精性脂肪性肝病(NAFLD)影响的妊娠率在过去十年中几乎翻了三倍,NAFLD 带来了增加的围产期风险,如高血压并发症、产后出血和早产。妊娠期间肝硬化的发生率也在上升,尽管缺乏特定于 NAFLD 肝硬化的估计。NAFLD 肝硬化是否比妊娠中其他原因的肝硬化带来不同的围产期风险也尚不清楚。

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