Torculas Maria, Medina Jethro, Xue Wei, Hu Xiao
Departments of Physics and Astronomy, ‡Electrical and Computer Engineering, ∇Mechanical Engineering, §Chemical Engineering, ∥Biomedical and Translational Sciences, and ⊥Biomedical Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
Departments of Physics and Astronomy, Electrical and Computer Engineering, ∇Mechanical Engineering, §Chemical Engineering, ∥Biomedical and Translational Sciences, and ⊥Biomedical Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States.
ACS Biomater Sci Eng. 2016 Aug 8;2(8):1211-1223. doi: 10.1021/acsbiomaterials.6b00119. Epub 2016 Jul 1.
The desire for flexible electronics is booming, and development of bioelectronics for health monitoring, internal body procedures, and other biomedical applications is heavily responsible for the growing market. Most current fabrication techniques for flexible bioelectronics, however, do not use materials that optimize both biocompatibility and mechanical properties. This Review explores flexible electronic technologies, fabrication methods, and protein materials for biomedical applications. With favorable sustainability and biocompatibility, naturally derived proteins are an exceptional alternative to synthetic materials currently used. Many proteins can take on various forms, such as fibers, films, and scaffolds. The fabrication of resistors and organic solar cells on silk has already been proven, and optoelectronics made of collagen and keratin have also been explored. The flexibility and biocompatibility of these materials along with their proven performance in electronics make them ideal materials in the advancement of biomedical devices.
对柔性电子产品的需求正在蓬勃发展，用于健康监测、体内手术及其他生物医学应用的生物电子学发展在很大程度上推动了市场的增长。然而，目前大多数用于柔性生物电子学的制造技术并未使用能同时优化生物相容性和机械性能的材料。本综述探讨了用于生物医学应用的柔性电子技术、制造方法和蛋白质材料。天然衍生的蛋白质具有良好的可持续性和生物相容性，是目前所用合成材料的绝佳替代品。许多蛋白质可以呈现各种形式，如纤维、薄膜和支架。在丝绸上制造电阻器和有机太阳能电池已得到证实，由胶原蛋白和角蛋白制成的光电子学也已得到探索。这些材料的柔韧性和生物相容性以及它们在电子学方面已被证实的性能，使其成为生物医学设备发展中的理想材料。
