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骨移植与非骨移植治疗跟骨骨折的疗效比较:一项荟萃分析方案。

Bone graft versus non-bone graft for treatment of calcaneal fractures: A protocol for meta-analysis.

机构信息

Department of Hand Surgery, The Second Hospital of Jilin University.

Center for Applied Statistical Research and College of Mathematics, Jilin University, Changchun, China.

出版信息

Medicine (Baltimore). 2021 Jan 15;100(2):e24261. doi: 10.1097/MD.0000000000024261.

Abstract

BACKGROUND

Calcaneal fractures are a prevalent form of injury caused by high-energy trauma. This study aimed at investigating whether bone graft and non-bone graft are essential for the internal fixation of calcaneal fractures. A meta-analysis of relevant clinical studies evaluated radiographic parameters, functional outcomes, and complications that offer practical recommendations on the suitability of bone grafts for the management of Calcaneal fractures.

METHODS AND ANALYSIS

This study performed a comprehensive search on PubMed, EMBASE, and Cochrane electronic to retrieve related clinical studies. The studies incorporated in our meta-analysis were identified after doing a preliminarily screening, reading of the full-text articles, and eliminating repeated studies. After quality assessment and data extraction, the standardized mean difference and risk ratio were selected as effect sizes. The data on Böhler angle, Gissane angle, calcaneal height, American Orthopaedic Foot and Ankle Society hindfoot scores, Maryland Foot Evaluation, and rate of wound infection were analyzed using Revman 5.3 software (Cochrane Collaboration).

RESULTS AND CONCLUSIONS

This study did not reveal any significant differences (P < .05) in both Böhler and Gissane angles, calcaneal height, American Orthopaedic Foot and Ankle Society hindfoot scores, Maryland foot evaluation, and rate of wound infection between the 2 groups. Due to the lack of a large sample of comparative studies, the use of bone grafting for the management of calcaneal fractures requires additional substantiation.

摘要

背景

跟骨骨折是一种常见的高能量创伤引起的损伤。本研究旨在探讨骨移植和非骨移植对内固定跟骨骨折是否必要。对相关临床研究进行荟萃分析,评估影像学参数、功能结果和并发症,为跟骨骨折的骨移植管理提供实用建议。

方法和分析

本研究在 PubMed、EMBASE 和 Cochrane 电子数据库中进行了全面检索,以检索相关的临床研究。我们的荟萃分析纳入的研究经过初步筛选、全文阅读和排除重复研究后确定。经过质量评估和数据提取,选择标准化均数差和风险比作为效应量。使用 Revman 5.3 软件(Cochrane 协作网)分析 Böhler 角、Gissane 角、跟骨高度、美国矫形足踝协会后足评分、马里兰足部评估和感染发生率的数据。

结果和结论

本研究未发现两组之间 Böhler 角和 Gissane 角、跟骨高度、美国矫形足踝协会后足评分、马里兰足部评估和感染发生率存在显著差异(P < .05)。由于缺乏大量的比较研究,骨移植在跟骨骨折治疗中的应用需要进一步证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d664/7808454/cb938cf8079c/medi-100-e24261-g001.jpg

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