Andelic Nada, Perrin Paul B, Forslund Marit V, Soberg Helene L, Sigurdardottir Solrun, Sveen Unni, Jerstad Tone, Roe Cecilie
Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway,
J Neurol. 2015 Mar;262(3):523-31. doi: 10.1007/s00415-014-7595-1. Epub 2014 Dec 5.
The aims of the study were to examine whether self-reported physical health changes over the first 5 years after traumatic brain injury (TBI), and whether the trajectories of physical health over that time period could be predicted by demographic and injury-related variables. A longitudinal cohort study was conducted with 97 individuals with moderate-to-severe TBI who had been admitted to a Trauma Referral Centre in 2005/2007. Patients were followed up at 1, 2 and 5 years post-injury. Physical health-related quality of life (HRQL) (i.e., physical health) was measured by four subscales of the Medical Outcomes 36-Item Short Form Health Survey (SF-36): Physical Functioning, Role-Physical, Bodily Pain and General Health. Only the Physical Functioning domain showed statistically significant improvements across time. Women had lower scores on Role-Physical, Bodily Pain (more pain) and General Health. Unemployment prior to injury and having been in a "blue collar" physical job was associated with lower Physical Functioning and General Health, while greater TBI severity was associated with lower Physical Functioning, but better Role-Physical. Bodily Pain, Role-Physical and General Health remained fairly stable over time, despite the improvement in Physical Functioning. There were a number of significant injury-related and demographic predictors across the four trajectories of physical health. A better understanding of factors influencing these domains over the first 5 years after TBI and effective pain reducing rehabilitation strategies are needed.
该研究的目的是检查创伤性脑损伤(TBI)后的头5年自我报告的身体健康是否发生变化,以及该时间段内的身体健康轨迹是否可以通过人口统计学和损伤相关变量进行预测。对97名中重度TBI患者进行了一项纵向队列研究,这些患者于2005/2007年入住创伤转诊中心。在受伤后1年、2年和5年对患者进行随访。通过医学结局简明健康调查问卷(SF-36)的四个子量表测量与身体健康相关的生活质量(HRQL)(即身体健康):身体功能、角色-身体、身体疼痛和总体健康。只有身体功能领域在各时间点显示出统计学上的显著改善。女性在角色-身体、身体疼痛(疼痛更严重)和总体健康方面得分较低。受伤前失业以及从事“蓝领”体力工作与较低的身体功能和总体健康相关,而更严重的TBI与较低的身体功能相关,但角色-身体方面较好。尽管身体功能有所改善,但身体疼痛、角色-身体和总体健康随时间保持相当稳定。在身体健康的四条轨迹上有许多与损伤相关和人口统计学的显著预测因素。需要更好地了解TBI后头5年影响这些领域的因素以及有效的疼痛减轻康复策略。