McNabb A W, Carroll W M, Mastaglia F L
Department of Neurology, Queen Elizabeth II Medical Centre, Perth, Western Australia.
J Neurol Neurosurg Psychiatry. 1988 Feb;51(2):218-22. doi: 10.1136/jnnp.51.2.218.
Three patients with dominant anterior cerebral artery territory infarction demonstrated a severe disturbance of upper limb motor control with impaired bimanual coordination, the "alien hand" sign, and intermanual conflict, in addition to signs of callosal interruption and a transcortical motor aphasia. Recordings of movement-related potentials in one patient showed an attenuated Bereitschaftspotential and a greater asymmetry of the NS' component of the premotor negativity with left finger than with right finger movement. The impairment of bimanual motor control and associated abnormal motor behaviour of the right hand in these cases are postulated to be due to involvement of the supplementary motor area and related areas of the medial frontal cortex.
三名大脑前动脉优势半球梗死患者除胼胝体中断和经皮质运动性失语的体征外，还表现出严重的上肢运动控制障碍，双手协调性受损，出现“异己手”征和双手冲突。对一名患者的运动相关电位记录显示， Bereitschaft电位减弱，运动前负波的NS成分在左手手指运动时比右手手指运动时更不对称。这些病例中双手运动控制受损及右手相关的异常运动行为被推测是由于辅助运动区和内侧额叶皮质相关区域受累所致。
