Piko Peter, Dioszegi Judit, Sandor Janos, Adany Roza
MTA-DE Public Health Research Group, University of Debrecen, 4032 Debrecen, Hungary.
Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
J Pers Med. 2021 Jan 16;11(1):52. doi: 10.3390/jpm11010052.
Metabolic syndrome (MetS) is a worldwide problem with severe health consequences. In this study, we examine the changes in the prevalence of MetS and its components in two disadvantaged counties of Northeastern Hungary. Two health examination surveys were performed in the Hungarian population aged 20-64 years in 2006 ( = 450) and 2018 ( = 397) and the data were compared to each other. It was found that the prevalence of MetS increased significantly in the period examined (from 34.9% to 42.2%, = 0.035) due to the increased prevalence of raised blood pressure (from 45.6% to 57.0%, = 0.002) and raised fasting glucose concentration (13.2% vs. 24.8%, < 0.001). The increase mainly affects the younger (20-34 years old) age group (12.1% in 2006 vs. 31.6% in 2018, = 0.001). It is quite alarming that the prevalence of MetS and its components has increased significantly in the last decade, while the prevalence of preventive medication is unchanged (antihypertensive and antidiabetic treatments) or even significantly decreased (lipid-lowering medication). Consequently, the number of individuals untreated for hypertension and metabolic disturbances is severely increased. A targeted public health strategy is desperately needed to prevent further worsening the situation.
代谢综合征(MetS)是一个全球性问题,会导致严重的健康后果。在本研究中,我们调查了匈牙利东北部两个贫困县代谢综合征及其各组分患病率的变化情况。2006年(n = 450)和2018年(n = 397)对匈牙利20 - 64岁人群进行了两次健康检查调查,并对数据进行了相互比较。结果发现,在所研究的时间段内,代谢综合征的患病率显著增加(从34.9%增至42.2%,P = 0.035),这是由于血压升高(从45.6%增至57.0%,P = 0.002)和空腹血糖浓度升高(13.2%对24.8%,P < 0.001)的患病率增加所致。这种增加主要影响较年轻的(20 - 34岁)年龄组(2006年为12.1%,2018年为31.6%,P = 0.001)。令人十分担忧的是,在过去十年中,代谢综合征及其各组分的患病率显著增加,而预防性药物治疗的患病率却没有变化(抗高血压和抗糖尿病治疗),甚至显著下降(降脂药物治疗)。因此,未接受高血压和代谢紊乱治疗的个体数量大幅增加。迫切需要制定有针对性的公共卫生策略以防止情况进一步恶化。