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2016 年匈牙利的抗血栓预防性药物处方开具与社会经济地位:一项横断面研究。

Antithrombotic Preventive Medication Prescription Redemption and Socioeconomic Status in Hungary in 2016: A Cross-Sectional Study.

机构信息

Public Health Administration Service of Government Office of Capital City Budapest, 1056 Budapest, Hungary.

Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.

出版信息

Int J Environ Res Public Health. 2020 Sep 19;17(18):6855. doi: 10.3390/ijerph17186855.

Abstract

This work was designed to investigate antithrombotic drug utilization and its link with the socioeconomic characteristics of specific population groups in Hungary by a comparative analysis of data for prescriptions by general practitioners and the redeemed prescriptions for antithrombotic drugs. Risk analysis capabilities were applied to estimate the relationships between socioeconomic status, which was characterized by quintiles of a multidimensional composite indicator (deprivation index), and mortality due to thromboembolic diseases as well as antithrombotic medications for the year 2016 at the district level in Hungary. According to our findings, although deprivation is a significant determinant of mortality due to thromboembolic diseases, clusters can be identified that represent exemptions to this rule: an eastern part of Hungary, consisting of two highly deprived counties, had significantly lower mortality than the country average; by contrast, the least-deprived northwestern part of the country, consisting of five counties, had significantly higher mortality than the country average. The fact that low socioeconomic status in general and poor adherence to antithrombotic drugs irrespective of socioeconomic status were associated with increased mortality indicates the importance of more efficient control of preventive medication and access to healthcare in all districts of the country to reduce mortality due to thromboembolic diseases.

摘要

这项工作旨在通过对全科医生处方数据和抗血栓药物 redeemed 处方进行比较分析,研究匈牙利特定人群群体的抗血栓药物利用情况及其与社会经济特征的关系。风险分析能力被应用于估计社会经济地位(用多维综合指标的五分位数来表示)与 2016 年匈牙利地区因血栓栓塞性疾病导致的死亡率以及抗血栓药物之间的关系。根据我们的发现,尽管贫困是导致血栓栓塞性疾病死亡的重要决定因素,但可以确定一些例外情况:匈牙利东部的两个高度贫困县组成的地区,其死亡率明显低于全国平均水平;相比之下,贫困程度最低的西北部地区(由五个县组成),其死亡率明显高于全国平均水平。一般来说,社会经济地位较低以及无论社会经济地位如何,抗血栓药物的依从性差与死亡率增加有关,这表明在该国所有地区更有效地控制预防药物和获得医疗保健对于降低因血栓栓塞性疾病导致的死亡率非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1ec/7559548/3dd33247e46f/ijerph-17-06855-g001.jpg

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