Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea; Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea.
Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea; Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea.
Alcohol. 2018 Sep;71:15-23. doi: 10.1016/j.alcohol.2018.01.005. Epub 2018 Feb 1.
This study investigated the relationship between drinking behavior (alcohol consumption frequency, average alcohol intake per drinking session) and the prevalence of metabolic syndrome (MetS) and its components (central obesity, raised triglycerides, decreased HDL cholesterol, raised blood pressure, raised fasting plasma glucose) in Korean men and women above the age of 20.
Our study employed data from the Korea National Health and Nutritional Examination Survey (KNHANES) for the years 2007-2013. The study population consisted of a total of 16,507 Korean males and 22,548 females; 30.0% (n = 4908) of all males and 29.8% (n = 6663) of all females were diagnosed with metabolic syndrome.
Relative to abstaining males, males who consumed alcohol more than 2-3 times per week (OR: 1.32, 95% CI: 1.04-1.66), as well as those who consumed more than 10 drinks per drinking session (OR: 1.71, 95% CI 1.41-2.08) had greatly increased odds risk of MetS. Alcohol consumption frequency was not associated with increased odds risk of MetS for females, however. Relative to abstaining females, females who consumed just 3-4 drinks per session had a 17% increased odds risk of MetS (OR: 1.17, 95% CI: 1.02-1.35). Females consuming more than 10 drinks per drinking session (OR: 1.91, 95% CI 1.44-2.52) were likely to have a 91% increase in odds risk of MetS. For males, alcohol consumption frequency was associated with high blood pressure and high fasting plasma glucose levels, while average alcohol intake per drinking session was associated with central obesity, high triglyceride levels, high blood pressure, and high fasting plasma glucose. For females, alcohol intake per session was associated with central obesity, high triglycerides, raised blood pressure, and high fasting plasma glucose.
Frequent alcohol consumption and high alcohol intake per drinking session were associated with higher prevalence of MetS and its components for Korean men; alcohol intake per drinking session only was associated with higher prevalence of MetS and its components for Korean women.
本研究旨在探讨韩国 20 岁以上男性和女性的饮酒行为（饮酒频率、每次饮酒的平均酒精摄入量）与代谢综合征（MetS）及其各组分（中心性肥胖、甘油三酯升高、高密度脂蛋白胆固醇降低、血压升高、空腹血糖升高）患病率之间的关系。
本研究采用了 2007-2013 年韩国国家健康和营养检查调查（KNHANES）的数据。研究人群共包括 16507 名韩国男性和 22548 名女性；其中 30.0%（n=4908）的男性和 29.8%（n=6663）的女性被诊断患有代谢综合征。
与不饮酒的男性相比，每周饮酒超过 2-3 次（OR：1.32，95%CI：1.04-1.66）和每次饮酒超过 10 杯（OR：1.71，95%CI：1.41-2.08）的男性患 MetS 的风险显著增加。然而，饮酒频率与女性患 MetS 的风险增加无关。与不饮酒的女性相比，每次饮酒 3-4 杯的女性患 MetS 的风险增加 17%（OR：1.17，95%CI：1.02-1.35）。每次饮酒超过 10 杯的女性患 MetS 的风险增加 91%（OR：1.91，95%CI：1.44-2.52）。对于男性，饮酒频率与高血压和空腹血糖升高有关，而每次饮酒的平均酒精摄入量与中心性肥胖、高甘油三酯水平、高血压和空腹血糖升高有关。对于女性，每次饮酒的酒精摄入量与中心性肥胖、高甘油三酯、血压升高和空腹血糖升高有关。
对于韩国男性，频繁饮酒和每次饮酒的酒精摄入量与 MetS 及其各组分的患病率较高有关；而对于韩国女性，仅每次饮酒的酒精摄入量与 MetS 及其各组分的患病率较高有关。
