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[1例对新辅助S-1加顺铂治疗病理完全缓解的胃癌病例]

[A Case of Gastric Cancer That Pathological Completely Responded to Neoadjuvant S-1 plus Cisplatin Therapy].

作者信息

Endo Ryoma, Sato Masaki, Akazawa Naoya, Yazawa Takashi, Tsuchiya Haruyuki, Sato Ryuichiro, Abe Tomoya, Okada Takaho, Kakita Tetsuya, Oikawa Masaya, Tsuchiya Takashi

机构信息

Dept. of Gastroenterological Surgery, Sendai Open Hospital.

出版信息

Gan To Kagaku Ryoho. 2020 Dec;47(13):1957-1959.

Abstract

A 67-year-old man with complaints of upper abdominal pain visited a clinic and was diagnosed with type 3 gastric cancer. Contrasted-enhanced CT revealed gastric wall thickening and extensive metastatic lymph nodes particularly around the celiac artery and also invasion to pancreas. He was diagnosed with cT4b, cN2, cM0, cStage ⅢB and we treated with neoadjuvant chemotherapy(NAC)consisting of 4 courses of S-1 and cisplatin regimen. After the NAC, primary cancer and metastatic lymph nodes were reduced remarkably. A curative operation could be performed and the histopathological examination showed"Grade 3, pathological complete response".

摘要

一名67岁男性因上腹部疼痛就诊,被诊断为3型胃癌。增强CT显示胃壁增厚,广泛的转移性淋巴结,尤其是在腹腔动脉周围,并且侵犯了胰腺。他被诊断为cT4b、cN2、cM0、cⅢB期,我们采用由4个疗程的S-1和顺铂方案组成的新辅助化疗(NAC)进行治疗。NAC后,原发性癌和转移性淋巴结明显缩小。可以进行根治性手术,组织病理学检查显示“3级,病理完全缓解”。

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