Division of Cardiac Surgery, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y4W7, Canada.
Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H8M5, Canada.
Sci Rep. 2021 Jan 19;11(1):1822. doi: 10.1038/s41598-020-80908-8.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in the death of millions. The COVID-19 pandemic has also resulted in a shortage of personal protective equipment (PPE) in many regions around the world, particularly in middle- and low-income countries. The shortages of PPE, such as N95 respirators, is something that will persist until an effective vaccine is made available. Thus, devices that while being easy to operate can also be rapidly deployed in health centers, and long-term residences without the need for major structural overhaul are instrumental to sustainably use N95 respirators. In this report, we present the design and validation of a decontamination device that combines UV-C & B irradiation with mild-temperature treatment. The device can decontaminate up to 20 masks in a cycle of < 30 min. The decontamination process did not damage or reduce the filtering capacity of the masks. Further, the efficacy of the device to eliminate microbes and viruses from the masks was also evaluated. The photothermal treatment of our device was capable of eradicating > 99.9999% of the bacteria and > 99.99% of the virus tested.
严重急性呼吸系统综合症冠状病毒 2(SARS-CoV-2)是引发 COVID-19 全球大流行的罪魁祸首,它已在全球范围内感染了超过 2500 万人,并导致数百万人死亡。COVID-19 大流行还导致全球许多地区,尤其是中低收入国家的个人防护设备(PPE)短缺。N95 口罩等 PPE 的短缺问题将持续存在,直到有有效的疫苗问世。因此,能够在卫生中心快速部署且无需大规模结构改造的简易操作设备对于可持续使用 N95 口罩至关重要。在本报告中,我们介绍了一种结合 UV-C 和 B 射线照射与温和温度处理的消毒设备的设计和验证。该设备可以在不到 30 分钟的循环内对多达 20 个口罩进行消毒。消毒过程不会损坏或降低口罩的过滤能力。此外,我们还评估了该设备从口罩中去除微生物和病毒的效果。我们设备的光热疗法能够消除测试的细菌中的>99.9999%和病毒中的>99.99%。