Department of Surgery, Faculty of Medicine, University of Colombo, P.O. Box 271, Kynsey Road, Colombo 8, Western Province, Sri Lanka.
World J Surg. 2021 Apr;45(4):1222-1236. doi: 10.1007/s00268-020-05923-2. Epub 2021 Jan 19.
Laser treatment is increasingly used in the treatment of symptomatic hemorrhoids, and several studies have attempted to describe its clinical outcomes. In this systematic review, we aimed to comprehensively analyze the clinical outcomes and effectiveness of laser treatment.
We performed a systematic review of currently available data on laser treatment for hemorrhoids. We searched MEDLINE and Google Scholar between January 2009 and May 2020. Studies that described the clinical outcomes and effectiveness of laser treatment were selected based on pre-specified inclusion criteria with a minimum follow-up period of 3 months. Qualitative synthesis of the clinical outcomes, effectiveness and complications was performed.
Nineteen studies including 1937 patients were analyzed. The majority were males (n = 1239) and included grade 2 and 3 hemorrhoids. In the majority (n = 1750, 90.34%), the 980 nm wave length diode laser was used as the energy source. Doppler-guided localization was performed in six studies (n = 579, 29.89%). All studies (n = 1937) reported low postoperative pain scores and nine studies (n = 1131) showed significantly lower pain compared to open technique. Furthermore, six studies (n = 1023) showed significantly less intra- and postoperative bleeding compared to open technique. Seven studies (n = 1052) reported long-term follow-up results and were found to be satisfactory in terms of symptom relief and recurrence. This study was limited by heterogeneity of outcomes precluding a meta-analysis.
Laser treatment had acceptable clinical outcomes for grade 2 and 3 hemorrhoids with lower rates of postoperative pain and bleeding with satisfactory long-term outcomes.
激光治疗在痔病的治疗中应用越来越广泛,有多项研究试图描述其临床效果。在本系统综述中,我们旨在全面分析激光治疗的临床效果和有效性。
我们对痔病激光治疗的现有数据进行了系统综述。我们在 2009 年 1 月至 2020 年 5 月期间在 MEDLINE 和 Google Scholar 上进行了搜索。根据预先设定的纳入标准选择描述了激光治疗的临床效果和有效性的研究,最低随访时间为 3 个月。对临床效果、有效性和并发症进行定性综合分析。
共分析了 19 项研究,纳入了 1937 例患者。多数为男性(n=1239),且纳入的痔病为 2 度和 3 度。在大多数情况下(n=1750,90.34%),使用 980nm 波长二极管激光作为能量源。6 项研究(n=579,29.89%)采用多普勒引导定位。所有研究(n=1937)均报告术后疼痛评分较低,9 项研究(n=1131)显示疼痛明显低于开放手术。此外,6 项研究(n=1023)显示术中及术后出血明显少于开放手术。7 项研究(n=1052)报告了长期随访结果,在缓解症状和复发方面均得到满意的结果。本研究受到结果异质性的限制,无法进行荟萃分析。
激光治疗 2 度和 3 度痔病的临床效果可接受,术后疼痛和出血发生率较低,长期效果满意。