Younis Muhammad Rizwan, He Gang, Lin Jing, Huang Peng
Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen 518060, People's Republic of China.
Biomed Mater. 2021 Feb 24;16(2):022007. doi: 10.1088/1748-605X/abdd6e.
Being a carbon-based hybrid, graphene-semiconductor composites have attracted considerable attention in recent decades owing to their potential features such as high photosensitivity, extended light absorption, and effective separation of charge carriers, thus have been regarded as a promising platform for environmental and biomedical applications, respectively. In this mini-review, we first summarized the recent advancements in the development of graphene-based semiconductor nanocomposites via sol-gel, solution mixing, in situ growth, hydrothermal, and solvothermal approaches, and then comprehensively reviewed their potential light activated cancer phototherapeutic applications. Finally, we rationally analyze the current challenges and new perspectives for the future development of more effective phototherapeutic nanoagents. We hope to offer enriched information to harvest the utmost fascinating properties of graphene as a platform to construct efficient graphene/semiconductor hybrids for cancer phototherapy.
作为一种碳基复合材料，石墨烯-半导体复合材料近几十年来因其高光敏性、扩展光吸收以及电荷载流子有效分离等潜在特性而备受关注，因此分别被视为环境和生物医学应用的一个有前景的平台。在本综述中，我们首先总结了通过溶胶-凝胶、溶液混合、原位生长、水热和溶剂热方法开发基于石墨烯的半导体纳米复合材料的最新进展，然后全面综述了它们在光激活癌症光治疗中的潜在应用。最后，我们合理分析了当前的挑战以及未来开发更有效的光治疗纳米剂的新前景。我们希望提供丰富的信息，以充分利用石墨烯作为构建用于癌症光治疗的高效石墨烯/半导体复合材料平台的最迷人特性。
