Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Department of Medicine, Faculty of Medicine and Health Sciences, University Malaysia Sarawak, Sarawak, Malaysia.
Singapore Med J. 2022 Jul;63(7):376-380. doi: 10.11622/smedj.2021003. Epub 2021 Jan 21.
Although erectile dysfunction (ED) is one of known long-term complications among male lymphoma survivors, it is not commonly reported, particularly in Southeast Asia. This study aimed to determine the prevalence of ED in lymphoma survivors in Malaysia and its association with anxiety and depression, and effects on quality of life.
This was a cross-sectional study conducted at a tertiary hospital in Malaysia. Patients were all male lymphoma survivors. The self-administered International Index of Erectile Function questionnaire was used to screen for ED. The Hospital Anxiety and Depression Score questionnaire was used to assess for anxiety and depression, and quality of life was assessed using the European Organization for Research and Treatment of Cancer quality of life questionnaire.
Overall, 106 patients were recruited. Mean age was 55.7 years, with 61.3% of patients aged above 50 years. Only 67.0% of patients were sexually active and 81.7% of these reported the presence of ED, with only 4.2% having severe ED. Prevalence of ED among younger patients (age ≤50 years old) was 64.5%.The most common reason given by patients who were not sexually active was fatigue. Age was the only factor found to be associated with ED (p <0.005) and severity of ED increased with age. There was no association between ED and psychological stress or quality of life.
Prevalence of ED and absence of sexual activity in lymphoma survivors was high. This should serve as a reminder to the treating clinician to offer early treatment and counselling.
尽管勃起功能障碍（ED）是男性淋巴瘤幸存者已知的长期并发症之一，但在东南亚，它并不常见。本研究旨在确定马来西亚淋巴瘤幸存者中 ED 的患病率及其与焦虑和抑郁的关系，并对生活质量的影响。
这是在马来西亚一家三级医院进行的横断面研究。患者均为男性淋巴瘤幸存者。采用自我管理的国际勃起功能指数问卷筛查 ED。采用医院焦虑抑郁量表评估焦虑和抑郁，采用欧洲癌症研究与治疗组织生活质量问卷评估生活质量。
共招募了 106 名患者。平均年龄为 55.7 岁，61.3%的患者年龄超过 50 岁。只有 67.0%的患者有性生活，其中 81.7%报告存在 ED，只有 4.2%的患者有严重 ED。年轻患者（≤50 岁）ED 的患病率为 64.5%。没有性生活的患者最常见的原因是疲劳。年龄是唯一与 ED 相关的因素（p<0.005），ED 的严重程度随年龄增加而增加。ED 与心理压力或生活质量之间没有关联。
淋巴瘤幸存者的 ED 患病率和无性生活发生率较高。这应提醒治疗医生早期提供治疗和咨询。
