Shafiee Nor Hamizah, Razalli Nurul Huda, Mokhtar Norfilza M, Tan Eunice, Ali Raja Affendi Raja
Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Dietetics Programme, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Intest Res. 2022 Jan;20(1):124-133. doi: 10.5217/ir.2020.00050. Epub 2021 Jan 22.
BACKGROUND/AIMS: Substantial proportions of patients with constipation-predominant irritable bowel syndrome (IBS-C) linked their symptoms with particular intake of foods. However, there is lack of current data regarding the intake among IBS-C patients before any dietary interventions. Thus, this study aimed to evaluate the dietary adequacy among IBS-C against the standard recommended nutrient intake (RNI) and healthy controls.
A retrospective case-control study was conducted involving IBS-C patients and healthy control subjects. A validated 126-food items frequency questionnaire was administered to all the subjects to assess their dietary intake, guided by dietitians. The calculated nutrients intake for IBS-C patients was then compared against the standard RNI and healthy controls.
A total of 306 subjects were recruited, among which 218 were diagnosed with IBS-C and 88 were included as healthy controls. IBS-C patients had significantly lower intake of wholegrain products, fried foods, dairy products, fruits, and vegetables compared to healthy controls. The daily intake of energy, certain macronutrients, and micronutrients among IBS-C patients was significantly lower than the healthy subjects. Less than 5% of IBS-C patients and healthy subjects achieved the standard recommendation for dietary fiber. Also, various vitamin intake (B1, B2, B6, folate, B12, E, K, and potassium) among IBS-C patients did not meet the standard RNI.
Dietary intakes of IBS-C patients did not meet the recommended intake for Malaysian and showed the nutritional inadequacies compared to the control subjects. Our study highlighted the importance of dietary evaluation prior to planning strategies for dietary intervention targeting IBS-C patients.
背景/目的：相当一部分以便秘为主的肠易激综合征（IBS-C）患者将其症状与特定食物摄入联系起来。然而，目前缺乏关于IBS-C患者在任何饮食干预之前的食物摄入量数据。因此，本研究旨在对照标准推荐营养素摄入量（RNI）评估IBS-C患者的饮食充足情况，并与健康对照者进行比较。
进行了一项回顾性病例对照研究，纳入IBS-C患者和健康对照者。在营养师的指导下，使用经过验证的包含126种食物的频率问卷对所有受试者进行调查，以评估他们的饮食摄入量。然后将IBS-C患者计算得出的营养素摄入量与标准RNI以及健康对照者进行比较。
共招募了306名受试者，其中218名被诊断为IBS-C，88名作为健康对照者。与健康对照者相比，IBS-C患者的全谷物产品、油炸食品、乳制品、水果和蔬菜摄入量显著较低。IBS-C患者的每日能量、某些宏量营养素和微量营养素摄入量显著低于健康受试者。不到5%的IBS-C患者和健康受试者达到膳食纤维的标准推荐量。此外，IBS-C患者的各种维生素摄入量（维生素B1、B2、B6、叶酸、B12、E、K和钾）未达到标准RNI。
IBS-C患者的饮食摄入量未达到马来西亚的推荐摄入量，与对照受试者相比显示出营养不足。我们的研究强调了在针对IBS-C患者制定饮食干预策略之前进行饮食评估的重要性。
