Health Sciences University, Bursa Yüksek İhtisas Training and Research Hospital, Orthopaedics and Traumatology Clinic, Bursa, Turkey.
Uludag University Faculty of Medicine, Department of Orthopaedics and Traumatology, Bursa, Turkey.
J Int Med Res. 2021 Jan;49(1):300060520984931. doi: 10.1177/0300060520984931.
This study was performed to investigate the baseline serum titanium levels in patients with short-segment titanium alloy posterior instrumentation and to assess patient-, implant-, and surgery-related factors that might affect the serum titanium level.
Two groups of patients were included in the study. The study group comprised 39 patients who had undergone short-segment posterior instrumentation from January 2013 to June 2016. The control group comprised 11 randomly selected patients who presented to the outpatient clinic with no history of orthopedic surgery. The serum titanium levels and inter-group differences were analyzed.
The mean serum titanium level was significantly higher in the study group than in the control group. No significant difference was observed between patients with different etiologies, implants used for fusion, numbers of instrumented segments, or postoperative durations.
The serum titanium levels of patients with posterior lumbar spinal instrumentation are significantly higher than those of the normal population even after achievement of solid fusion. These levels are not affected by the use of transverse connectors, the use of cages, the operated segments, or the duration of implants.
本研究旨在调查短节段钛合金后路内固定术后患者的血清钛基线水平，并评估可能影响血清钛水平的患者、植入物和手术相关因素。
本研究纳入两组患者。研究组包括 2013 年 1 月至 2016 年 6 月期间接受短节段后路内固定的 39 例患者。对照组包括 11 例随机选择的门诊就诊、无骨科手术史的患者。分析血清钛水平和组间差异。
研究组患者的血清钛平均水平明显高于对照组。不同病因、融合使用的植入物、节段数或术后时间的患者之间无显著差异。
即使达到牢固融合，后路腰椎脊柱内固定患者的血清钛水平仍明显高于正常人群。这些水平不受横向连接器的使用、笼的使用、手术节段或植入物的持续时间的影响。
