Blizard Institute, Barts Brain Tumour Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK
Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
Development. 2021 Jan 20;148(2):dev193342. doi: 10.1242/dev.193342.
Brain tumours are the commonest solid neoplasms in children, accounting for one quarter of all childhood cancers. Our growing knowledge of basic developmental mechanisms has significantly contributed to understanding the pathogenesis of these tumours and is beginning to impact clinical decisions on how children with these diseases are treated.
脑肿瘤是儿童中最常见的实体肿瘤，占所有儿童癌症的四分之一。我们对基本发育机制的认识不断提高，这对理解这些肿瘤的发病机制有重大贡献，并开始影响如何治疗患有这些疾病的儿童的临床决策。
