Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
J Clin Microbiol. 2021 Mar 19;59(4). doi: 10.1128/JCM.02252-20.
Whole-genome sequences of isolates from nosocomial and nonnosocomial infections were compared. The average numbers of single nucleotide variations were different between the two groups. The small amount of genetic variability between intra- or interhost isolates suggests recovery of all colonizing or infecting genomes for comparison is required for outbreaks.
对来自医院内和医院外感染的 分离株的全基因组序列进行了比较。两组之间的单核苷酸变异数量存在差异。同一宿主或不同宿主之间分离株的遗传变异性较小,这表明需要对所有定植或感染的基因组进行回收,以便进行暴发比较。