Efficacy of Dupilumab in Concomitant Atopic Dermatitis and Chronic Rhinosinusitis With Nasal Polyps: A Preliminary Study.
作者信息
Nettis Eustachio, Patella Vincenzo, Brancaccio Raffaele, Detoraki Caterina, Di Leo Elisabetta, Incorvaia Cristoforo, Macchia Luigi, Pellacani Giovanni, Bonzano Laura
机构信息
Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari Aldo Moro, Bari, Italy.
Division of Allergy and Clinical Immunology, Department of Medicine ASL Salerno, "Santa Maria della Speranza" Hospital, Battipaglia, Salerno, Italy.
出版信息
Allergy Asthma Immunol Res. 2021 Mar;13(2):347-349. doi: 10.4168/aair.2021.13.2.347.
Abstract
摘要
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Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.度普利尤单抗治疗伴有鼻息肉的重度慢性鼻-鼻窦炎患者的疗效和安全性（LIBERTY NP SINUS-24 和 LIBERTY NP SINUS-52）：两项多中心、随机、双盲、安慰剂对照、平行分组 3 期临床试验的结果。
Lancet. 2019 Nov 2;394(10209):1638-1650. doi: 10.1016/S0140-6736(19)31881-1. Epub 2019 Sep 19.
2
Biologics for the treatment of chronic rhinosinusitis with nasal polyps - state of the art.用于治疗伴鼻息肉的慢性鼻-鼻窦炎的生物制剂——最新进展
World Allergy Organ J. 2019 Aug 9;12(8):100050. doi: 10.1016/j.waojou.2019.100050. eCollection 2019 Aug.
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