Zhongguo Dang Dai Er Ke Za Zhi. 2021 Jan;23(1):1-11. doi: 10.7499/j.issn.1008-8830.2011145.
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease of neonates, especially of preterm infants, with high morbidity and mortality. The surviving infants may have digestive tract and neurological sequelae. Therefore, the prevention and treatment of NEC are of great significance in improving survival rate and survival quality of neonates. To provide evidence-based recommendations for management of NEC, the guidelines were developed based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) and the current domestic and overseas studies.
坏死性小肠结肠炎(NEC)是一种严重的新生儿胃肠道疾病,尤其是早产儿,其发病率和死亡率很高。存活的婴儿可能会有消化道和神经后遗症。因此,NEC的防治对提高新生儿的存活率和生存质量具有重要意义。为了为NEC的管理提供循证建议,本指南基于推荐评估、制定与评价分级(GRADE)以及当前国内外研究制定。