Institute for Epidemiology, Social Medicine and Health Systems Research, Hannover Medical School, Hannover, Germany
Institute for Epidemiology, Social Medicine and Health Systems Research, Hannover Medical School, Hannover, Germany.
BMJ Open. 2021 Jan 21;11(1):e042399. doi: 10.1136/bmjopen-2020-042399.
In Germany, the organised colorectal cancer (CRC) screening programme includes the immunologic faecal occult blood test and colonoscopy. The sigmoidoscopy is recommended for individuals rejecting colonoscopy but is not included into the screening programme. To examine whether the evidence based sigmoidoscopy should be additionally offered, the first objective of this study is to evaluate the demand for sigmoidoscopy by analysing the German general populations' preferences for CRC screening.
Preference data will be collected using a discrete choice experiment (DCE). Identification and selection of the attributes and their levels will be supported by evidence resulting from a systematic literature search and focus groups. An efficient, fractional factorial choice design will be generated. In a cross-sectional study, the DCE will be administered as a written questionnaire to a random sample of 4000 members of the statutory health insurance company in Lower Saxony (AOK Lower Saxony). Insured persons 50-60 years of age without CRC or a chronic inflammatory bowel disease will be eligible. The collected choice data will be analysed by conducting a conditional logit regression model and latent class models.
Ethical approval for this study was obtained from the Ethics Committee of Hannover Medical School (reference number 8671_BO_K_2019). The study results will be disseminated via conference presentations, publications in peer-reviewed journals and, to participants, the membership magazine of the AOK Lower Saxony.
DRKS00019010.
在德国，组织化的结直肠癌（CRC）筛查计划包括免疫粪便潜血试验和结肠镜检查。对于拒绝结肠镜检查的个体，推荐进行乙状结肠镜检查，但该检查不包含在筛查计划中。为了研究是否应该额外提供基于证据的乙状结肠镜检查，本研究的首要目标是通过分析德国普通人群对 CRC 筛查的偏好来评估对乙状结肠镜检查的需求。
偏好数据将通过离散选择实验（DCE）收集。属性及其水平的识别和选择将得到系统文献检索和焦点小组的证据支持。将生成一个有效的、分数阶的因子设计。在一项横断面研究中，DCE 将作为书面问卷分发给下萨克森州法定健康保险公司（AOK 下萨克森）的 4000 名随机样本。年龄在 50-60 岁之间、没有 CRC 或慢性炎症性肠病的参保人员符合条件。通过进行条件逻辑回归模型和潜在类别模型分析收集的选择数据。
本研究已获得汉诺威医学院伦理委员会的批准（编号 8671_BO_K_2019）。研究结果将通过会议演讲、同行评议期刊发表以及 AOK 下萨克森会员杂志向参与者传播。
DRKS00019010。
