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炎症作为冠状动脉支架植入术后愈合反应的一个决定因素。

Inflammation as a determinant of healing response after coronary stent implantation.

作者信息

Ochijewicz Dorota, Tomaniak Mariusz, Opolski Grzegorz, Kochman Janusz

机构信息

1st Department of Cardiology, Medical University of Warsaw, Banacha 1a Str., 02-097, Warsaw, Poland.

出版信息

Int J Cardiovasc Imaging. 2021 Mar;37(3):791-801. doi: 10.1007/s10554-020-02073-3. Epub 2021 Jan 21.

Abstract

Cardiovascular disease remains the leading cause of death and morbidity worldwide. Inflammation plays an important role in the development of atherosclerosis and is associated with adverse clinical outcomes in patients after percutaneous coronary interventions. Data on stent elements that lead to excessive inflammatory response, proper identification of high-risk patients, prevention and treatment targeting residual inflammatory risk are limited. This review aims to present the role of inflammation in the context of evolving stent technologies and appraise the potential imaging modalities in detection of inflammatory response and anti-inflammatory therapies.

摘要

心血管疾病仍然是全球范围内死亡和发病的主要原因。炎症在动脉粥样硬化的发展过程中起着重要作用,并且与经皮冠状动脉介入治疗后患者的不良临床结局相关。关于导致过度炎症反应的支架因素、高危患者的正确识别以及针对残余炎症风险的预防和治疗的数据有限。本综述旨在阐述炎症在不断发展的支架技术背景下的作用,并评估检测炎症反应和抗炎治疗的潜在成像方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be7/7969567/c7f5581023cf/10554_2020_2073_Fig1_HTML.jpg

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