Tunis Med. 2020 Dec;98(12):972-979.
Depression is a major burden for the health-care system worldwide. It is important to use standardized and easily applicable tools for large-scale population screening to improve the early detection of depression. The PHQ-9 has been recommended as the best available screening and case-finding instrument based on its brevity and ability to inform the clinicians on both depression severity and diagnostic criteria.
To evaluate the reliability and the validity of the Tunisian version of the PHQ-9 in the general population in Tunisia; the Tunisian version of the Hospital anxiety depression scale (HAD) was used as the gold standard for major depression diagnosis.
We undertook a cross-sectional, descriptive and analytical study. A total of 134 participants were enrolled. The PHQ-9 was validated against the HAD reference standard.
Test-Retest reliability was determined by intraclass correlation. This scale was stable over 2 weeks (ICC=0,97).The Tunisian version of the PHQ-9 has a good internal reliability (Cronbach's alpha = 0.84). As for criterion validity of the PHQ-9, the Pearson's correlation coefficient between the PHQ-9 and HAD was 0.94 and the Spearman's correlation coefficient was 0,81. A cut-off score of 10 had a sensitivity of 86,2 and a specificity of 83,8. The VPP was 0,6 and the VPN was 0,9. The prevalence of depression in ours ample was 13,4%. There were no statistical difference in gender, education and age for the prevalence of depression.
The Tunisan version of the PHQ-9 is a valid and reliable casefinding instrument for detecting depression.
抑郁症是全球医疗保健系统的主要负担。使用标准化且易于应用的工具对大规模人群进行筛查，对于提高抑郁症的早期发现至关重要。PHQ-9 因其简洁性和能够为临床医生提供抑郁严重程度和诊断标准的信息而被推荐为最佳的筛查和病例发现工具。
评估 PHQ-9 突尼斯版本在突尼斯普通人群中的可靠性和有效性；使用医院焦虑抑郁量表（HAD）的突尼斯版本作为主要抑郁症诊断的金标准。
我们进行了一项横断面、描述性和分析性研究。共有 134 名参与者入组。PHQ-9 针对 HAD 参考标准进行了验证。
通过组内相关系数确定了重测信度。该量表在 2 周内保持稳定（ICC=0.97）。PHQ-9 的突尼斯版本具有良好的内部可靠性（Cronbach's alpha=0.84）。至于 PHQ-9 的标准效度，PHQ-9 与 HAD 之间的 Pearson 相关系数为 0.94，Spearman 相关系数为 0.81。截断值为 10 时，灵敏度为 86.2%，特异性为 83.8%。VPP 为 0.6，VPN 为 0.9。我们样本中的抑郁症患病率为 13.4%。性别、教育程度和年龄对抑郁症的患病率没有统计学差异。
PHQ-9 的突尼斯版本是一种有效的、可靠的病例发现工具，可用于检测抑郁症。
