Salah Nouran Yousef, Hashim Mostafa Ahmad, Abdeen Mai Seif ElDin
Department of Pediatrics, Faculty of Medicine, Ain Shams University, 25 Korash Street, Nasr City, Cairo, Egypt.
Department of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
J Eat Disord. 2022 Apr 4;10(1):46. doi: 10.1186/s40337-022-00571-4.
Disordered eating behaviour (DEB) represents a significant morbidity among people with type-1 diabetes (T1D). Continuous-subcutaneous insulin infusion (CSII) improves glycemic control and psychological wellbeing in those with T1D. However, its relation to DEB remains obscure.
To compare DEB among adolescents with T1D on CSII versus basal-bolus regimen and correlate it with body image, HbA1C and depression.
Sixty adolescents with T1D (30 on CSII and 30 on basal-bolus regimen), aged 12-17 years were studied focusing on diabetes-duration, insulin therapy, exercise, socioeconomic standard, hypoglycemic attacks/week and family history of psychiatric illness. Anthropometric measures, HbA1C, binge eating scale (BES), body image tool, patient health questionnaire-9 (PHQ9) and the Mini-KID depression scale were assessed.
Among the studied adolescents with T1D, six had DEB (10%), 14 had poor body-image perception (23.3%), 42 had moderate body-image perception (70%) and 22 had depression (36.7%). Adolescents with T1D on CSII had significantly lower BES (p = 0.022), Mini-KID depression (p = 0.001) and PHQ9 (p = 0.02) than those on basal-bolus regimen. BES was positively correlated to depression (p < 0.001), HbA1C (p = 0.013) and diabetes-duration (p = 0.009) and negatively correlated to body-image (p = 0.003).
DEB is a prevalent comorbidity among adolescents with T1D, with higher frequency in those on basal-bolus regimen than CSII.
饮食行为紊乱（DEB）在1型糖尿病（T1D）患者中是一种严重的发病情况。持续皮下胰岛素输注（CSII）可改善T1D患者的血糖控制和心理健康。然而，其与DEB的关系仍不明确。
比较接受CSII治疗与基础-餐时胰岛素治疗方案的T1D青少年的DEB情况，并将其与身体意象、糖化血红蛋白（HbA1C）和抑郁相关联。
对60名年龄在12至17岁的T1D青少年（30名接受CSII治疗，30名接受基础-餐时胰岛素治疗方案）进行研究，重点关注糖尿病病程、胰岛素治疗、运动、社会经济水平、每周低血糖发作次数以及精神疾病家族史。评估人体测量指标、HbA1C、暴饮暴食量表（BES）、身体意象工具、患者健康问卷9项（PHQ9）和儿童简易抑郁量表。
在研究的T1D青少年中，6人有DEB（10%），14人身体意象感知较差（23.3%），42人身体意象感知中等（70%），22人有抑郁（36.7%）。接受CSII治疗的T1D青少年的BES（p = 0.022）、儿童简易抑郁量表得分（p = 0.001）和PHQ9得分（p = 0.02）显著低于接受基础-餐时胰岛素治疗方案的青少年。BES与抑郁（p < 0.001）、HbA1C（p = 0.013）和糖尿病病程（p = 0.009）呈正相关，与身体意象呈负相关（p = 0.003）。
DEB在T1D青少年中是一种常见的合并症，基础-餐时胰岛素治疗方案组的发生率高于CSII组。
