Chemical Biology Unit, Institute of Nano Science & Technology, Mohali, Punjab 160062, India.
Cell and Molecular Biology Division, AAL Research & Solutions Pvt. Ltd., Panchkula, Haryana 134113, India.
Nanomedicine (Lond). 2021 Jan;16(2):139-163. doi: 10.2217/nnm-2020-0314. Epub 2021 Jan 22.
Molecular self-assembly is a widespread natural phenomenon and has inspired several researchers to synthesize a compendium of nano/microstructures with widespread applications. Biomolecules like proteins, peptides and lipids are used as building blocks to fabricate various nanomaterials. Supramolecular peptide self-assembly continue to play a significant role in forming diverse nanostructures with numerous biomedical applications; however, dipeptides offer distinctive supremacy in their ability to self-assemble and produce a variety of nanostructures. Though several reviews have articulated the progress in the field of longer peptides or polymers and their self-assembling behavior, there is a paucity of reviews or literature covering the emerging field of dipeptide-based nanostructures. In this review, our goal is to present the recent advancements in dipeptide-based nanostructures with their potential applications.
分子自组装是一种广泛存在的自然现象，激发了许多研究人员合成具有广泛应用的纳米/微结构。生物分子如蛋白质、肽和脂质被用作构建块来制造各种纳米材料。超分子肽自组装继续在形成具有众多生物医学应用的各种纳米结构方面发挥重要作用;然而，二肽在自组装和产生各种纳米结构的能力方面具有独特的优势。尽管有几篇综述阐述了较长肽或聚合物及其自组装行为领域的进展，但很少有综述或文献涵盖基于二肽的纳米结构这一新兴领域。在这篇综述中，我们的目标是介绍基于二肽的纳米结构的最新进展及其潜在应用。
