Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.
Protein Pept Lett. 2020;27(8):688-697. doi: 10.2174/0929866527666200212123542.
Supramolecular self-assembled functional materials comprised of cyclic dipeptide building blocks have excellent prospects for biotechnology applications due to their exceptional structural rigidity, morphological flexibility, ease of preparation and modification. Although the pharmacological uses of many natural cyclic dipeptides have been studied in detail, relatively little is reported on the engineering of these supramolecular architectures for the fabrication of functional materials. In this review, we discuss the progress in the design, synthesis, and characterization of cyclic dipeptide supramolecular nanomaterials over the past few decades, highlighting applications in biotechnology and optoelectronics engineering.
由环二肽构建块组成的超分子自组装功能材料由于其出色的结构刚性、形态灵活性、易于制备和修饰，在生物技术应用方面具有广阔的前景。尽管许多天然环二肽的药理学用途已经得到了详细研究，但关于这些超分子结构的工程用于制造功能材料的报道相对较少。在本文中，我们讨论了过去几十年中环二肽超分子纳米材料的设计、合成和表征方面的进展，重点介绍了它们在生物技术和光电子工程中的应用。
