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纳米技术在抗击新冠病毒中的应用:预防、治疗与诊断。

Nanotechnology Enabled Solutions to Combat Covid-19: Prevention, Treatment, and Diagnosis.

机构信息

Delhi Pharmaceutical Sciences and Research University, New Delhi-110017,India.

Chitkara College of Pharmacy, Chitkara University, Punjab,India.

出版信息

Curr Pharm Biotechnol. 2022;23(1):98-111. doi: 10.2174/1389201022666210122124311.

Abstract

Changes in human lifestyles and environmental deterioration globally cause the emergence of new viruses, posing research challenges. The outburst of COVID-19 (nCoV19) is a recent example, wherein effective management of virus, using the conventional medication and effective diagnostic measures is a challenge. While many ongoing strategies from vaccine development to drug repurposing are currently being investigated, a targeted approach with nanotechnology can be helpful to meet the demand for preventive and diagnostic measures. The significant results of nanotechnology in providing better efficacy of pharmaceutical drugs is expected to combat nCoV19 by using nanotechnology- based solutions, preventive treatment, and diagnosis. This article addresses the dire need for nanotechnology-based solutions in the current pandemic, as well as analyzes the ongoing innovation and existing patents that can be used to provide better solutions. Multiple applications of nanotechnology are considered to be helpful in preventive and diagnostic measures, immune response modulation, and immunity boosters, along with projecting a pathway for industry and academic researchers for addressing such a pandemic.

摘要

全球范围内人类生活方式的改变和环境恶化导致新病毒的出现,这给研究带来了挑战。COVID-19(nCoV19)的爆发就是一个最近的例子,其中使用传统药物和有效诊断措施来有效管理病毒是一个挑战。虽然目前正在研究从疫苗开发到药物再利用的许多正在进行的策略,但采用纳米技术的靶向方法可能有助于满足预防和诊断措施的需求。纳米技术在提高药物疗效方面的显著成果有望通过使用基于纳米技术的解决方案、预防治疗和诊断来对抗 nCoV19。本文讨论了当前大流行中对基于纳米技术的解决方案的迫切需求,并分析了正在进行的创新和现有专利,这些创新和专利可用于提供更好的解决方案。考虑到纳米技术在预防和诊断措施、免疫反应调节和免疫增强剂方面的多种应用,为行业和学术研究人员提供了一条应对此类大流行的途径。

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