Niu Yumin, Wang Bin, Yang Runhui, Wu Yongning, Zhao Yunfeng, Li Cuizhi, Zhang Jing, Xing Yang, Shao Bing
Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Chinese Academy of Inspection and Quarantine Comprehensive Test Center, Beijing 100123, China.
J Agric Food Chem. 2021 Feb 3;69(4):1391-1397. doi: 10.1021/acs.jafc.0c06938. Epub 2021 Jan 22.
Concentrations of bisphenol A (BPA) and its analogues (together with their chlorinated derivatives are referred to as BPs) were measured in 181 breastmilk samples collected from 9 provinces in China in 2014. Twelve BP types were found. The BP concentrations ranged from not detected to 5.912 μg/L. BPA was the predominant BP, followed by bisphenol F (BPF) and bisphenol S (BPS). The mean BPA, BPF, and BPS levels were 0.444, 0.107, and 0.027 μg/L, respectively. Other BPs were sporadically detected in breastmilk samples. There were no differences ( > 0.05) in BPA, BPF, BPS, or total BP levels in the urban and rural regions or the northern and southern regions. BPA accounted for approximately 70% of the BPs and BPF accounted for more than 20% of the BPs in breast milk samples. The high contribution of BPF indicated that BPA analogues, not only BPA, should receive attention. The upper-bound daily intakes of BPs for infants 0-6 months old were 0.044-1.291 μg/kg bw/day. Despite the absence of tolerable daily intake data, attention should be paid not only on BPA but also BPF.
2014年，在中国9个省份采集的181份母乳样本中，测定了双酚A（BPA）及其类似物（其氯化衍生物统称为BPs）的浓度。共检测出12种BPs类型。BPs浓度范围为未检出至5.912μg/L。双酚A是主要的BPs，其次是双酚F（BPF）和双酚S（BPS）。双酚A、双酚F和双酚S的平均水平分别为0.444μg/L、0.107μg/L和0.027μg/L。其他BPs在母乳样本中偶尔被检测到。城市和农村地区以及北方和南方地区的双酚A、双酚F、双酚S或总BPs水平没有差异（P>0.05）。在母乳样本中，双酚A约占BPs的70%，双酚F占BPs的20%以上。双酚F的高占比表明，不仅双酚A，双酚A类似物也应受到关注。0至6个月大婴儿的BPs每日摄入量上限为0.044-1.291μg/kg体重/天。尽管缺乏每日耐受摄入量数据，但不仅应关注双酚A，还应关注双酚F。
