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儿童和青少年头颈部肿瘤:多学科肿瘤委员会的影响。

Head and neck tumors in children and adolescents: Impact of a multidisciplinary tumor board.

机构信息

Université de Paris, NeuroDiderot, Inserm, 75019 Paris, France; Pediatric Ear, Nose, and Throat Department, Robert Debré Hospital, Public Assistance-Hospitals of Paris, Paris, France.

SIREDO Oncology Center (Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer), PSL Research University, Institut Curie, Paris, France.

出版信息

Oral Oncol. 2021 Mar;114:105145. doi: 10.1016/j.oraloncology.2020.105145. Epub 2021 Jan 20.

DOI:10.1016/j.oraloncology.2020.105145
PMID:33482589
Abstract

INTRODUCTION

Cancer treatment in France is based on Multidisciplinary Tumor Board (MTB). In the Ile-de-France region (IDF), which includes 12 million inhabitants from Paris and the surrounding area, pediatric tumors of head and neck are discussed since 2013 in a dedicated Interregional Pediatric Multicentric MTB (IPMTB). The purpose of this study is to analyze the impact of the IDF head and neck IPMTB on the management of these tumors, 5 years after their implementation.

MATERIALS AND METHODS

Retrospective study of all patient files presented in the IPMTB for a benign or malignant head-and-neck tumor, between 2013 and 2018.

RESULTS

A total of 679 discussions were analyzed representing 428 patients. Median age was 7.5 years (range: 0-31 years). Malignant tumors represented 71% of cases, including 36% of rhabdomyosarcoma. Overall, 12% percent of the cases discussed came from centers outside of IDF. All meetings complied with multidisciplinary criteria required by French law. Proposals made during the IPMTB were followed in 86% of cases. Among the 251 proposals made by the referring teams prior to the IPMTB, 29% were secondarily modified after being discussed in the IPMTB.

CONCLUSION

Thanks to their multidisciplinarity, high number of cases discussed and usual respect of their proposals, the IPMTB have made it possible to improve the coordination between all specialties involved in the patient's management, to apply the most recent and scientifically validated protocols, and to share the knowledge of different teams concerning the management of particularly rare tumors.

摘要

简介

法国的癌症治疗基于多学科肿瘤委员会(MTB)。在包括巴黎及其周边地区 1200 万居民的法兰西岛大区(IDF),自 2013 年以来,专门的区域性儿科多中心 MTB(IPMTB)讨论了头颈部儿科肿瘤。本研究旨在分析 IDF 头颈部 IPMTB 对这些肿瘤管理的影响,这是在实施 5 年后进行的。

材料和方法

回顾性分析了 2013 年至 2018 年间在 IPMTB 中提交的所有良性或恶性头颈部肿瘤患者的病历。

结果

共分析了 679 次讨论,涉及 428 名患者。中位年龄为 7.5 岁(范围:0-31 岁)。恶性肿瘤占 71%,包括 36%的横纹肌肉瘤。总体而言,12%的讨论病例来自 IDF 以外的中心。所有会议均符合法国法律要求的多学科标准。86%的病例遵循了 IPMTB 提出的建议。在 IPMTB 之前由转介团队提出的 251 项建议中,29%在 IPMTB 讨论后被修改。

结论

由于其多学科性、讨论的大量病例以及通常尊重其建议,IPMTB 使得协调参与患者管理的所有专业变得更加容易,能够应用最新的、经过科学验证的方案,并共享不同团队在管理特别罕见肿瘤方面的知识。

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