Popa V
Medical College of Ohio, Toledo 43699.
Ann Allergy. 1988 Mar;60(3):203-6.
We report the beneficial effect of steroids in a 27-year-old woman with lymphocytic interstitial pneumonitis (LIP) and common variable immunodeficiency (CVID). Exertional dyspnea, x-ray infiltrates, and pulmonary physiologic abnormalities decreased or increased during 3 1/2 years of follow-up in parallel with the administered dose of prednisone. This observation rules out concomitant spontaneous remission as the explanation of steroid-induced improvement of LIP in CVID. Steroid treatment was apparently safe: the frequency and severity of recurrent bronchial infections did not change, although IgG replacement therapy was not provided.
我们报告了类固醇对一名患有淋巴细胞性间质性肺炎（LIP）和常见可变免疫缺陷（CVID）的27岁女性的有益作用。在3年半的随访中，运动性呼吸困难、X线浸润和肺生理异常随泼尼松给药剂量的变化而相应减轻或加重。这一观察结果排除了同时出现的自发缓解作为类固醇诱导CVID中LIP改善的解释。类固醇治疗显然是安全的：尽管未提供IgG替代疗法，但复发性支气管感染的频率和严重程度并未改变。
