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益生菌对 COVID-19 患者结局的潜在有益作用:不断发展的观点。

Potential beneficial role of probiotics on the outcome of COVID-19 patients: An evolving perspective.

机构信息

Department of Interdisciplinary Medicine, Microbiology and Virology Unit, Medical School, University of Bari "Aldo Moro", Policlinico University Hospital of Bari, p.zza G. Cesare 11, 70124, Bari, Italy; Department of Clinical Disciplines, School of Technical Medical Sciences, "A. Xhuvani" University of Elbasan, Rruga Ismail Zyma, 3001, Elbasan, Albania.

Department of Interdisciplinary Medicine, Dentistry Unit, Medical School, University of Bari "Aldo Moro", Policlinico University Hospital of Bari, p.zza G. Cesare 11, 70124, Bari, Italy.

出版信息

Diabetes Metab Syndr. 2021 Jan-Feb;15(1):295-301. doi: 10.1016/j.dsx.2020.12.040. Epub 2021 Jan 13.

Abstract

BACKGROUND AND AIMS

Probiotics can support the body's systems in fighting viral infections. This review is aimed to focus current knowledge about the use of probiotics as adjuvant therapy for COVID-19 patients.

METHODS

We performed an extensive research using the PubMed-LitCovid, Cochrane Library, Embase databases, and conducting manual searches on Google Scholar, Elsevier Connect, Web of Science about this issue.

RESULTS

We have found several papers reporting data about the potential role of probiotics as well as contrasting experimental data about it.

CONCLUSIONS

Most data show good results demonstrating that probiotics can play a significant role in fighting SARS-CoV-2 infection, also compared with their use in the past for various diseases. They seem effective in lowering inflammatory status, moreover in patients with chronic comorbidities such as cancer and diabetes, improving clinical outcomes.

摘要

背景和目的

益生菌可以支持身体系统对抗病毒感染。本综述旨在关注益生菌作为 COVID-19 患者辅助治疗的最新知识。

方法

我们使用 PubMed-LitCovid、Cochrane 图书馆、Embase 数据库进行了广泛的研究,并在 Google Scholar、Elsevier Connect、Web of Science 上对这个问题进行了手动搜索。

结果

我们发现了几篇报告关于益生菌的潜在作用的数据,以及一些对比性的实验数据。

结论

大多数数据表明益生菌在对抗 SARS-CoV-2 感染方面可以发挥重要作用,与过去用于治疗各种疾病的效果相比也很好。它们似乎可以有效降低炎症状态,此外,对于患有癌症和糖尿病等慢性合并症的患者,还可以改善临床结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a9/7804381/e93760dff770/gr1_lrg.jpg

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