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评估住院和门诊环境中 COVID-19 患者的眼部症状。

Evaluation of ocular symptoms in COVID-19 subjects in inpatient and outpatient settings.

机构信息

Ophthalmology Department, University of the Health Sciences, Umraniye Training and Research Hospital, İstanbul, Turkey.

Ophthalmology Department, University of Auckland, Auckland, New Zealand.

出版信息

Int Ophthalmol. 2021 Apr;41(4):1541-1548. doi: 10.1007/s10792-021-01728-x. Epub 2021 Jan 24.

Abstract

PURPOSE

Evaluation of subtle ocular involvement and clinically significant conjunctivitis symptoms in a group of patients with COVID-19 in outpatient and inpatient settings.

METHOD

Overall, 1083 patients infected with SARS-CoV-2 were recruited as subjects. Patients were divided into inpatients (group 1, n = 371) and outpatients (group 2, n = 712). Demographical and general medical data included age, sex, and comorbidities. Patients whose diagnosis was confirmed by reverse-transcriptase polymerase chain reaction (RT-PCR) were called by phone, and their chronic ocular disease, previous ocular surgery, ocular medication, contact lens wear and ocular irritation symptoms were queried during the active disease period.

RESULTS

The mean age of the patients was 44.2 ± 16.5 (19-97) years; 635 (58.6%) were male, and 448 (41.4%) were female. Comorbidity, chronic ocular disease, ophthalmic medication and previous ocular surgery rates were significantly higher in group 1 (p < 0.05), while contact lens wear was not significantly different between groups. The main complaints received from patients were sore eye or burning sensation, foreign body sensation, itching and red eye and were significantly higher in group 1. Clinically significant conjunctivitis symptoms, such as red eye, ocular discharge and eyelid edema, were observed in 28 patients (2.6%), with 14 (3.8%) patients in group 1 and 14 (2%) patients in group 2.

CONCLUSION

Clinically significant conjunctivitis symptoms were detected in 28 subjects in the inpatient and outpatient groups. As systemic findings of COVID-19 intensify.

摘要

目的

评估门诊和住院环境中一组 COVID-19 患者的细微眼部受累和有临床意义的结膜炎症状。

方法

共招募了 1083 名感染 SARS-CoV-2 的患者作为研究对象。患者分为住院患者(第 1 组,n=371)和门诊患者(第 2 组,n=712)。人口统计学和一般医学数据包括年龄、性别和合并症。通过逆转录酶聚合酶链反应(RT-PCR)确诊的患者通过电话联系,并在疾病活跃期询问他们的慢性眼病、既往眼部手术、眼部用药、隐形眼镜佩戴和眼部刺激症状。

结果

患者的平均年龄为 44.2±16.5(19-97)岁;635 名(58.6%)为男性,448 名(41.4%)为女性。第 1 组的合并症、慢性眼病、眼科用药和既往眼部手术率明显更高(p<0.05),而两组间隐形眼镜佩戴率无显著差异。患者的主要主诉是眼痛或烧灼感、异物感、瘙痒和眼红,第 1 组明显更高。观察到 28 例(2.6%)患者出现有临床意义的结膜炎症状,如眼红、眼部分泌物和眼睑水肿,第 1 组 14 例(3.8%),第 2 组 14 例(2%)。

结论

在住院和门诊患者组中发现了 28 例有临床意义的结膜炎症状。随着 COVID-19 的全身表现加重。

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