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测量全球、地区和国家 2 型糖尿病的负担,以及在所有 194 个国家/地区的所有可归因危险因素。

Measuring the global, regional, and national burden of type 2 diabetes and the attributable risk factors in all 194 countries.

机构信息

Department of Endocrinology, People's Hospital of Yuyao, Ningbo, China.

Department of Geriatrics and Traditional Chinese Medicine, People's Hospital of Yuyao, Ningbo, China.

出版信息

J Diabetes. 2021 Aug;13(8):613-639. doi: 10.1111/1753-0407.13159. Epub 2021 Feb 12.

DOI:10.1111/1753-0407.13159
PMID:33486878
Abstract

BACKGROUND

No detailed quantitative global, regional, or national estimates of the disability-adjusted life years (DALYs) of type 2 diabetes mellitus (T2DM) are available.

METHODS

We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 to estimate the global, regional, and national incidence rates and DALYs of T2DM, as well as the associated risk factors, in all 194 countries and territories by age, sex, and sociodemographic status during the period from 2007 to 2017.

RESULTS

Globally, the age-standardized incidence and DALY rates increased by 3.23% and 5.07% during 2007 to 2017, respectively. The age-standardized incidence and DALY rates in 2017 and the corresponding percentage changes during 2007 to 2017 were highest in the low-middle sociodemographic index (SDI) quintile. Regionally, the highest 2017 age-standardized incidence and DALY rates were observed in Oceania, whereas the largest percentage increases in both rates during 2007 to 2017 were observed in Southeast Asia. Nationally, Iran, the United Kingdom, and Indonesia reported the largest percentage increases in the age-standardized incidence rates, whereas Georgia, Czech Republic, and Iran showed the largest percentage increases in the age-standardized DALY rates. Globally, the largest percentage increases in risk-attributable DALYs were associated with a high body mass index, low physical activity level, high fasting plasma glucose level, and high sugar-sweetened beverage and red meat consumption.

CONCLUSIONS

The global T2DM age-standardized incidence and DALY rates increased globally between 2007 and 2017, especially in the low-middle SDI quintile, Southeast Asia.

摘要

背景

目前尚无关于 2 型糖尿病(T2DM)伤残调整生命年(DALYs)的详细全球、区域或国家估计值。

方法

我们使用 2017 年全球疾病、伤害和危险因素研究(GBD)的数据,估计了 2007 年至 2017 年期间全球 194 个国家和地区按年龄、性别和社会人口统计学地位划分的 T2DM 发病率和 DALYs 以及相关危险因素。

结果

全球范围内,2007 年至 2017 年期间,年龄标准化发病率和 DALY 率分别上升了 3.23%和 5.07%。2017 年的年龄标准化发病率和 DALY 率以及 2007 年至 2017 年期间的相应百分比变化在中低收入社会人口指数(SDI)五分位数中最高。在区域一级,2017 年发病率和 DALY 率最高的是大洋洲,而发病率和 DALY 率在 2007 年至 2017 年期间的增幅最大的是东南亚。在国家一级,伊朗、英国和印度尼西亚报告了年龄标准化发病率的最大百分比增长,而格鲁吉亚、捷克共和国和伊朗则显示了年龄标准化 DALY 率的最大百分比增长。全球范围内,与高体重指数、低体力活动水平、高空腹血糖水平以及高含糖饮料和红色肉类消费相关的可归因风险 DALY 百分比增幅最大。

结论

2007 年至 2017 年期间,全球 T2DM 的年龄标准化发病率和 DALY 率均有所上升,尤其是在中低收入 SDI 五分位数中,以及东南亚地区。

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